Schork-Lab / tanner

Code related to the tanner project
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Modeling: Identification of change points #4

Open kunalbhutani opened 9 years ago

kunalbhutani commented 9 years ago

To look at differences in trends that might indicative of a change. Find changepoint that show a difference in mean or variance after a time point.

kunalbhutani commented 9 years ago

Using the R package: http://www.jstatsoft.org/v58/i03/paper

kunalbhutani commented 9 years ago

Example of Median Stability

run6-2-eicosatrienoylglycerophosphocholine -log run6-2-eicosatrienoylglycerophosphocholine -median run6-2-eicosatrienoylglycerophosphocholine -zscore

Example of Median Agreeing with Z-score instead of Raw

run6-2-hydroxyhippurate salicylurate -log run6-2-hydroxyhippurate salicylurate -median run6-2-hydroxyhippurate salicylurate -zscore

Since we are going to manually tagging these anyways, these distinctions might not matter.

kunalbhutani commented 9 years ago

It would be interesting to see multivariate changepoints in terms of maybe certain pathways. This can be explored through another R-package: http://arxiv.org/pdf/1309.3295.pdf