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ShellyCoder / cellcall

inferring cell-cell communication from scRNA-seq of ligand-receptor
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could this software be used to compare two or more treatment? #15

Open Baoquan-Han opened 2 years ago

Baoquan-Han commented 2 years ago

hello, thanks a lot. I want to use this software to compare the difference between the two treatments, could you add the solutions? @ShellyCoder

realzehuali commented 2 years ago

I tried to group my cells with ident label that contains the information of both group and treatment. for example: seurat$celltype = paste(seurat$treatment, seurat$Group, sep="_") and then transform this seurat into cellcall object.

ShellyCoder commented 2 years ago

I hope this would not be late for this reply.

Sorry for the defect when docking the Seurat S4 object. We recommend preprocessing your data in advance.

At the same time, the data of multiple treatments may need to be applied to cellcall, respectively, according to different groups, and then compared with each other according to their communication scoring results.

There is no yet embedded method for analysis of diferent groups.

Sorry for this inconvience. Thanks !