Shicheng-Guo / rbiotools

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Converting mouse to human gene names with biomaRt package #6

Open Shicheng-Guo opened 3 years ago

Shicheng-Guo commented 3 years ago

Mouse gene to human gene

musGenes <- c("Hmmr", "Tlx3", "Cpeb4")
# Basic function to convert mouse to human gene names
convertMouseGeneList <- function(x){
require("biomaRt")
human = useMart("ensembl", dataset = "hsapiens_gene_ensembl")
mouse = useMart("ensembl", dataset = "mmusculus_gene_ensembl")
genesV2 = getLDS(attributes = c("mgi_symbol"), filters = "mgi_symbol", values = x , mart = mouse, attributesL = c("hgnc_symbol"), martL = human, uniqueRows=T)
humanx <- unique(genesV2[, 2])
# Print the first 6 genes found to the screen
print(head(humanx))
return(humanx)
}

Human gene to mouse gene

# Basic function to convert human to mouse gene names
convertHumanGeneList <- function(x){
require("biomaRt")
human = useMart("ensembl", dataset = "hsapiens_gene_ensembl")
mouse = useMart("ensembl", dataset = "mmusculus_gene_ensembl")
genesV2 = getLDS(attributes = c("hgnc_symbol"), filters = "hgnc_symbol", values = x , mart = human, attributesL = c("mgi_symbol"), martL = mouse, uniqueRows=T)
humanx <- unique(genesV2[, 2])
# Print the first 6 genes found to the screen
print(head(humanx))
return(humanx)
}
genes <- convertMouseGeneList(humGenes)

Reference: https://www.r-bloggers.com/2016/10/converting-mouse-to-human-gene-names-with-biomart-package/