Construct pharmacogenomics (PGx) polygenic risk score (PRS) with PRS-PGx-Unadj (unadjusted), PRS-PGx-CT (clumping and thresholding), PRS-PGx-L, -GL, -SGL (penalized regression), PRS-PGx-Bayes (Bayesian regression). Package is based on ”Pharmacogenomics Polyenic Risk Score for Drug Response Prediction Using PRS-PGx Methods” by Zhai, S., Zhang, H., Mehrotra, D.V., and Shen, J., 2021 (submitted).
Construct pharmacogenomics (PGx) polygenic risk score (PRS) with PRS-PGx-Unadj (unadjusted), PRS-PGx-CT (clumping and thresholding), PRS-PGx-L, -GL, -SGL (penalized regression), PRS-PGx-Bayes (Bayesian regression). Package is based on ”Pharmacogenomics Polyenic Risk Score for Drug Response Prediction Using PRS-PGx Methods” by Zhai, S., Zhang, H., Mehrotra, D.V., and Shen, J., 2021 (submitted).