ShixiangWang / gcap

GCAP (Gene-level Circular Amplicon Prediction) firstly implements extrachromosomal DNA detection from whole-exome-sequencing (WES) data and absolute copy number profiles. https://shixiangwang.r-universe.dev/gcap
https://shixiangwang.github.io/gcap/
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The output file of gcap.ASCNworkflow #49

Open GetOutofBug opened 2 months ago

GetOutofBug commented 2 months ago

A object record: 213 case: 2 | (0) 56 noncircular | (2) 157 circular

Excuse me, does this mean that 2 of the 157 looped DNA could be ecDNA? So how do I find these two cases?

ShixiangWang commented 2 months ago

Record (213, including 56 noncircular records plus 157 records) means how many focal amplified genes found in the data, Case means 2 samples were analyzed. Based the analysis, two samples were assigned to circular class as both of them have circular records.

For the result object, check https://shixiangwang.github.io/gcap/reference/fCNA.html