repairSig - Githubissues

ShixiangWang / sigminer

🌲 An easy-to-use and scalable toolkit for genomic alteration signature (a.k.a. mutational signature) analysis and visualization in R https://shixiangwang.github.io/sigminer/reference/index.html

https://shixiangwang.github.io/sigminer/

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repairSig #390

Closed ShixiangWang closed 2 years ago

ShixiangWang commented 3 years ago

https://github.com/ncbi/RepairSig

ShixiangWang commented 2 years ago

Key idea:

DNA Damage (additive)
Deficient DNA Repair (non-additive)

RepairSig models the mutational landscape as a composition of DNA damage and repair