Simon-Coetzee / motifBreakR

A Package For Predicting The Disruptiveness Of Single Nucleotide Polymorphisms On Transcription Factor Binding Sites.
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Any plans to include a p value for the affinity score change between the two alleles? #42

Open NCTrailRunner opened 2 years ago

NCTrailRunner commented 2 years ago

First, thank you so much for making this outstanding software available to the bioinformatics community. I have been working with the new version that handles indels for a project examining transcription factor binding in the development of Alzheimer's disease and greatly appreciate the new functions to handle indels. The program is extremely powerful. Do you have plans to eventually include a p value calculation for the affinity score change that you report? This would be a great addition. Thank you for considering.