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Stortebecker / metabolomics

A repo to exchange and discuss metabolomics issues at the ZBSA Freiburg.
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Problems already solved for Proteomics #7

Open Stortebecker opened 7 years ago

Stortebecker commented 7 years ago

When we do have the basics, these ideas which are commonly used in proteomics could be transferred to metabolomics:

  1. Establishing a database with common contaminants, analogue to the "CRAP" database for proteomics.
  2. Determining the FDR for IDs with a list of true negatives (i.e. fake database entries), analogue to the reversed databases in proteomics. Check, how this problem is solved when using proteomics spectral libraries.
  3. Advanced / automated improvement of spectral databases, analogue to algorithms like SpecraST