The adduct formed between RA-0001351 and protected cysteine was synthesized using the reaction shown below. Details of this experiment can be found here. The adduct was characterized using NMR and LCMS. Please find the SMILES representations of RA-0001351 and the adduct below.
The adduct formed between RA-0001351 and protected cysteine was synthesized using the reaction shown below. Details of this experiment can be found here. The adduct was characterized using NMR and LCMS. Please find the SMILES representations of RA-0001351 and the adduct below.
RA-0001351:
O=C(C=C/1C)C=C(C)C1=N/OS(=O)(C2=CC=C(Cl)C=C2)=Oadduct:O=C(C=C/1C)C=C(C)C1=N/SC[C@H](NC(C)=O)C(OC)=O