An SGC Chemical Networks Project devoted to the DENV Rdrp, focusing specifically on exploring the Enamine covalent library. Use the link below to learn about other READDI-AViDD projects.
The 11 compounds from the first expansion have been tested by Jessica Smith at single-point (10 μM) in the nano-luciferase antiviral assay. 4 compounds have been move to dose-response, antiviral replication, and cytotoxicity tests.
May 31 2024
The 11 compounds from the first expansion have been tested by Jessica Smith at single-point (10 μM) in the nano-luciferase antiviral assay. 4 compounds have been move to dose-response, antiviral replication, and cytotoxicity tests.