They actually conflict with the option _HD44780I2C = 0 on the esp8266/esp-open-rtos/examples/hd44780_lcd/Makefile.
On the other hand if no option is added to the Makefile, the component.mk file on folder /esp8266/esp-open-rtos/extras/hd44780 declares it as:
HD44780_I2C ?= 1
As such there is no issue totally deleting these 3 lines.
There is no reason of the following 3 lines:
They actually conflict with the option _HD44780I2C = 0 on the esp8266/esp-open-rtos/examples/hd44780_lcd/Makefile.
On the other hand if no option is added to the Makefile, the component.mk file on folder /esp8266/esp-open-rtos/extras/hd44780 declares it as: HD44780_I2C ?= 1
As such there is no issue totally deleting these 3 lines.