remove non-metabolic genes from Protein assembly and degradation subsystems

[haowang-bioinfo]

Description of the issue:

• Non-metabolic genes are discovered in the GPR rules of following reactions in Protein assembly and Protein degradation subsystems:

gene	Reasons	Subsystems	RxnIDs
ENSG00000131400	No enough supporting evidence, may be involved in processing of pneumocyte surfactant precursors	Protein degradation	MAR05259;MAR05261;MAR05263;MAR05265;MAR05272;MAR05274;MAR05276;MAR05278;MAR05280;MAR05282;MAR05284;MAR05285;MAR05286;MAR05287;MAR05289;MAR05290
ENSG00000196136	no enough supporting evidence	Protein assembly	MAR05152
ENSG00000197249	annotated as Inhibitor of serine proteases, not related to protein assembly	Protein assembly	MAR05153

Current feature/value/output:

• The association of these genes is lack of evidence according to the provided reasons

Expected feature/value/output:

• Remove above genes from Human-GEM

I hereby confirm that I have:

• [X] Done this analysis in the main branch of the repository
• [X] Checked that a similar issue does not exist already

[feiranl]

LGTM!

[haowang-bioinfo]

The deletion of ENSG00000196136 and ENSG00000197294 is suspended. Because they are the only genes involved in reactions MAR05152 and MAR05153, respectively. Re-inspection is needed before further removal.