SysBioChalmers / Human-GEM

The generic genome-scale metabolic model of Homo sapiens
https://sysbiochalmers.github.io/Human-GEM-guide/
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ChatGPT GitHub Action for gene-associated modification #483

Open feiranl opened 1 year ago

feiranl commented 1 year ago

Description of the issue:

We are thinking that we can make ChatGPT as github action so that it can double check the modification made in the pull request.

1) Go to Uniprot extract the annotation for the modified gene 2) check wether the gene is associated with the subsystem and the substrates 3) according to the output, then define pass/fail for the model modification

mihai-sysbio commented 1 year ago

Some more clarifications would be appreciated:

mihai-sysbio commented 1 year ago

Here is a random example with ChatGTP:

image

And here is another one from the OpenAI API:

image
mihai-sysbio commented 1 year ago

And here is the Bing answer to the same question (balanced version):

image

and the more precise answer:

image
feiranl commented 2 months ago

@guozhetao Could you handle this task?

mihai-sysbio commented 2 months ago

In my previous tests with publicly-available AI models, the responses I would get were not trustworthy. I'd be curious to see how this changed since, and perhaps if the question can be formulated differently for a more accurate answer.

feiranl commented 2 months ago

Yes, it seems much better right now with the development of LLMs. Will update soon.