MAR03432 fully β-oxidizes 13,16,19-docosatrienoyl-CoA to acetyl-CoA in a single step, and MAR03431 fully β-oxidizes (11Z,14Z,17Z)-eicosatrienoyl-CoA to acetyl-CoA in a single step. One round of β-oxidation of 13,16,19-docosatrienoyl-CoA would produce (11Z,14Z,17Z)-eicosatrienoyl-CoA, and another would produce linolenoyl-CoA (AKA (9Z,12Z,15Z)-octadecatrienoyl-CoA, MAM02390m). Since the β-oxidation of linolenoyl-CoA is already represented by the long series of reactions outlined in #765, MAR03431 and MAR03432 are partially redundant with those reactions. I think a relatively straightforward remedy to this situation would be to edit each of them to only represent a single round of β-oxidation each:
[ ] Edit MAR03432 to be 13,16,19-docosatrienoyl-CoA + FAD + H2O + NAD+ + CoA -> (11Z,14Z,17Z)-eicosatrienoyl-CoA + FADH2 + NADH + H+ + acetyl-CoA, GPR: (ACAD9 or ACADL or ACADVL) and HADHA and HADHB
[ ] Edit MAR03431 to be (11Z,14Z,17Z)-eicosatrienoyl-CoA + FAD + H2O + NAD+ + CoA -> linolenoyl-CoA + FADH2 + NADH + H+ + acetyl-CoA, GPR: (ACAD9 or ACADL or ACADVL) and HADHA and HADHB
MAR03432fully β-oxidizes 13,16,19-docosatrienoyl-CoA to acetyl-CoA in a single step, andMAR03431fully β-oxidizes (11Z,14Z,17Z)-eicosatrienoyl-CoA to acetyl-CoA in a single step. One round of β-oxidation of 13,16,19-docosatrienoyl-CoA would produce (11Z,14Z,17Z)-eicosatrienoyl-CoA, and another would produce linolenoyl-CoA (AKA (9Z,12Z,15Z)-octadecatrienoyl-CoA,MAM02390m). Since the β-oxidation of linolenoyl-CoA is already represented by the long series of reactions outlined in #765,MAR03431andMAR03432are partially redundant with those reactions. I think a relatively straightforward remedy to this situation would be to edit each of them to only represent a single round of β-oxidation each:MAR03432to be 13,16,19-docosatrienoyl-CoA + FAD + H2O + NAD+ + CoA -> (11Z,14Z,17Z)-eicosatrienoyl-CoA + FADH2 + NADH + H+ + acetyl-CoA, GPR:(ACAD9 or ACADL or ACADVL) and HADHA and HADHBMAR03431to be (11Z,14Z,17Z)-eicosatrienoyl-CoA + FAD + H2O + NAD+ + CoA -> linolenoyl-CoA + FADH2 + NADH + H+ + acetyl-CoA, GPR:(ACAD9 or ACADL or ACADVL) and HADHA and HADHB