SysBioChalmers / ecModels

A container for all enzyme constrained models created by GECKO.
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update eciML1515 based on 2021-02-27-17-57 #68

Closed automator-metatlas closed 3 years ago

automator-metatlas commented 3 years ago
MATLAB is selecting SOFTWARE OPENGL rendering.
WARNING: Potentially problematic ") AND (" in the grRules for reaction(s): 
    PFL
    RNDR1
    RNDR3
    RNDR4
    CITL
    NO3R1bpp
    NO3R2bpp
    ATPS4rpp
    CPGNtonex
    ...and 19 more

WARNING: The following metabolite names begin with a number directly followed by space:
    2doxg6p_c
    3amp_p
    3cmp_p
    2dglc_p
    3cmp_e
    3ump_e
    2dglc_e
    3amp_e
    3ump_p
    2dglc_c

***************************************************************
   GECKO: Adding enzyme constraints to a genome-scale model
***************************************************************

Getting genome-scale model ready... Done!

==================
Generating ecModel:
==================
Retrieving EC numbers............................... Done!
Matching kcats............................... Done!
Adding enzymes to reactions........................................ Done!
Improving model with curated data...Improving model with curated data
............................................................. Done!
Removing repeated rxn: THMDt2pp_copy1 & THMDt2pp_copy2
Removing repeated rxn: URIt2pp_copy1 & URIt2pp_copy2
Removing repeated rxn: ADNt2pp_copy1 & ADNt2pp_copy2
Removing repeated rxn: GLCtex_copy1 & GLCtex_copy2
Removing repeated rxn: CYTDt2pp_copy1 & CYTDt2pp_copy2

==============================================================
Generating ecModel with shared pool assumption (ecModel_batch):
==============================================================
Calculating total abundance............................................Matching data to enzymes in model... Done!
Total protein amount measured = 0 g/gDW
Total enzymes measured = 0 enzymes
Enzymes in model with 0 g/gDW = 0 enzymes
Total protein amount not measured = 0.5793 g/gDW
Total enzymes not measured = 1259 enzymes
Total protein in model = 0.5793 g/gDW
The ECmodel is overconstrained!
******************* Limiting Kcats curation *******************
*Iteration #1
 Automatic search // EC#: 6.3.5.3
  Protein:P15254 Rxn#:2574 name: Phosphoribosylformylglycinamidine synthase (No1)
  prev_Kcat:0.05 new_Kcat:5.0675 CC:2.3159 Err:21.2491%
***************************************************************
Fitting sigma factor....................... Done!
[Warning: MATLAB has disabled some advanced graphics rendering features by switching to software OpenGL. For more information, click <a href="matlab:opengl('problems')">here</a>.] 
Saving simulation results files...
File successfully saved.
Sigma factor (fitted for growth on glucose): 0.41

=============
Saving models:
=============
Saving eciML15152021-02-27-17-57:
Converting RAVEN structure to COBRA..
Each model.subSystems{x} is a character array, and this format is retained.
Document written
Each model.subSystems{x} is a character array, and this format is retained.
Saving eciML1515_batch2021-02-27-17-57:
Converting RAVEN structure to COBRA..
Each model.subSystems{x} is a character array, and this format is retained.
Document written
Each model.subSystems{x} is a character array, and this format is retained.