GWAS based Simulation

[olivierlabayle]

Use GWAS hits as variants for the generating process

• [x] Variant Selection

  • [x] Enable fixing some variants a priori (use defined estimands to enforce them?)
  • [x] pvalue threshold
  • [x] linkage disequilibrium threshold : R squared of 1 megabase away?
  • [x] total number of variant threshold?

• [x] Estimands Selection

  • [x] Think about something, probably hardcoded from pre selected variants.

• [x] Integrate in workflows

• [x] trial run