search

TKMarkCheng / NormaliseForIC50

pre-process data to return normalise IC50 curves for direct input into PRISM
https://tkmarkcheng.github.io/NormaliseForIC50/
MIT License
0 stars 1 forks source link

Calculate IC50 and verify against PRISM's value #14

Open TKMarkCheng opened 6 months ago

TKMarkCheng commented 6 months ago

Is your feature request related to a problem? Please describe. A natural extension of this project - doing the IC50 for the user without the need of PRISM.

Describe the solution you'd like

  1. Uses a correct curve fitting tool - currently on PRISM the 4-parameter logistical fit curve is used (https://www.mdpi.com/2409-9279/1/1/8)
  2. Plot all curves for visualisation, and flag outstanding values (IC50 outside the upper/lower detection limits)
  3. Return IC50 to table according to user-defined groups (V2.0)
TKMarkCheng commented 5 months ago

A good package to use is the drc package