TRON-Bioinformatics / covigator-ngs-pipeline

A Nextflow pipeline for NGS variant calling on SARS-CoV-2. From FASTQ files to normalized and annotated VCF files from GATK, BCFtools, LoFreq and iVar.
MIT License
18 stars 7 forks source link

Different pangolin lineages given variant caller #63

Open GoncheDanesh opened 11 months ago

GoncheDanesh commented 11 months ago

Hi,

First, thank you for this great tool. I have a list of different pipelines to test, and yours is the only one that got installed and runs easily!

I ran your pipeline on my fastq files and in the results directory I got different fasta files, one for each VCF file as explained. All of them except for the lofreq resulted as a BA.2 lineage et the lofreq one was B.1.1.529.

How do I know which tool's results I should keep?

Thanks, Best