Tarela / SELMA

Intrinsic bias estimation for improved analysis of bulk and single-cell chromatin accessibility profiles using SELMA
GNU Affero General Public License v3.0
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Few bug fixes #3

Closed iaaka closed 2 years ago

iaaka commented 2 years ago

Hi, thank you very much for this excellent tool. I encountered several problems (that I believe were caused by bugs) when I attempted to apply it to 10x single cell atac data. I managed to fix these bugs and I think it would be great to include these corrections into future releases.

First, I was unable to install it under python3.9, so I added conda-based instruction into README on how to install it using python3.6, it would save me half of hour, so I believe it is useful. Second, I updated file name check to allow .tsv.gz files that are normally output by cellranger and modified functions to skip header lines (started with '#') in fragment files. And finally, I fixed path to twoBitInfo_linux