match/mismatch accuracy on simulations

Teichlab / Genes2Genes

Aligning gene expression trajectories of single-cell reference and query systems

https://teichlab.github.io/Genes2Genes/

MIT License

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match/mismatch accuracy on simulations #2

Open emdann opened 1 year ago

emdann commented 1 year ago

Added notebook with:

functions to split dataset in reference and query simulating mismatch (deletions/insertions) in the query, of different lengths and starts
Code to compute "match prediction accuracy" (i.e. in which fraction of bins does the alignment correctly identify a match or a mismatch?)
Test on pancreas dataset using 5 genes picked from the CellRank paper.

emdann commented 1 year ago

Insertion/deletion accuracy results are saved in:

/nfs/team205/ed6/bin/Genes2Genes/notebooks/data/match_accuracy_pancreas.insertion.csv
/nfs/team205/ed6/bin/Genes2Genes/notebooks/data/match_accuracy_pancreas.deletion.csv