potential workflow for MultiMAP.Integration for cross species analysis

Teichlab / MultiMAP

MultiMAP for integration of single cell multi-omics

MIT License

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potential workflow for MultiMAP.Integration for cross species analysis #8

Open deevdevil88 opened 2 years ago

deevdevil88 commented 2 years ago

Hi, I had a quick question in regards to using MultiMAP for cross species analysis, should I only have the 1:1 orthologues between the two species in each of the AnnData objects, or can i also have unshared features?

Best, Devika

ktpolanski commented 2 years ago

That's a neat application of MultiMAP!

You're welcome to have unshared features as well, and use those to compute the single-species dataset reductions. The transcriptomics plus ATAC integration in the demo has some number of unique features for each modality.

deevdevil88 commented 2 years ago

Great! We will try it with unshared features then. Thanks for getting back to me . Best, Devika