Notes from first look at cell2location alphatesting - Githubissues

Teichlab / Pan_fetal_immune

Collection of scripts for analysis of pan fetal immune atlas

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Notes from first look at cell2location alphatesting #39

Closed emdann closed 2 years ago

emdann commented 2 years ago

Observations

what is that south aggreagate in thymus sample? B1/Cycling B rich, NK rich...
Spatial segregation between quiescent DN/DP and proliferative DN/DP in thymus? Factor 1 and 9 in n_fact10

Questions

How much does the scale of factors matters?

Next steps

Do stromal cell types by organs match more consistently to the organ?
What stromal/immune interactions can we pick up?
Best strategy for selecting NMF model? (total variance explained estimate?)