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Teichlab / cellphonedb

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The ligand and receptor on dotplot issue #352

Closed honghh2018 closed 2 years ago

honghh2018 commented 3 years ago

Hi developer, It make me confused about the ligand and receptor dotplot. the picture showing below:

image

whether the first gene separated by "_" definitely was the ligand like the red frame on above plot. Nonetheless, if i guess right, the gene Pdgfra was abbreviation of 'Platelet Derived Growth Factor Receptor Alpha' . Clearly, It should be the ligand but receptor. So, the dotplot in row gene pairs had ambiguous ligand-receptor pairs. It was so difficult to distinct which gene belong to ligand or receptor.

Hope you help me to determine the dotplot result. Best, Hanhuihong

MISAKA-DaYu commented 3 years ago

企业微信截图_a230c813-1a0f-43f1-9953-0233317629e0 It seems like interacting_pair has no direction, it can be ligand-receptor, or receptor-ligand. Details can be found in means.txt file, receptor_a or receptor_b column.