Hi, I'm using cellphonedb database generate --user-interactions my_interaction.txt to generate a custom database. There are some complex in my own interaction file. But I encountered difficulty. For example, S100A8 and S100A9 formed heterodimer to interact with TLR4. If the my_interaction.txt inputed as the following, the new database include two interaction, which means S100A8 and S100A9 interact with TLR4 separately. But actually, there are only one interactions. How can I get the correct database? How can I prepare my interaction input file?
Hi, I'm using cellphonedb database generate --user-interactions my_interaction.txt to generate a custom database. There are some complex in my own interaction file. But I encountered difficulty. For example, S100A8 and S100A9 formed heterodimer to interact with TLR4. If the my_interaction.txt inputed as the following, the new database include two interaction, which means S100A8 and S100A9 interact with TLR4 separately. But actually, there are only one interactions. How can I get the correct database? How can I prepare my interaction input file?