Teichlab / tracer

TraCeR - reconstruction of T cell receptor sequences from single-cell RNAseq data
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How to match my TCR sequence reported by TraCer with my 10X Cellranger vdj output Clonalcall? #120

Open MugenQin opened 2 years ago

MugenQin commented 2 years ago

Hi, Thanks for your effort for developing TraCer! It's very convenient for us to get the clonotypes. Now I want to project my single cell full-length TCR to my 10X scRNA+TCR seq data. So I need to match them through the same TCR sequence. After reading your paper, I know that TraCer reported V genes & junction sequences & J genes. But 10X cellranger VDJ can report VDJ gens or CDR3 sequences. I got the puzzle about how to use the output sequences of both softwares and match them. Could you give me some advice? Thanks Qin