Closed hkoohy closed 5 years ago
Hi Mike, Sorry to bother you again for another question: In our tracer output (cell data file where we see clone groups and sizes), for some cells we both productive A and B chain, but the clonal_group and 'group_size' is left blanked! Does this mean that the chains are unpaired? please see the following for an example: many thanks
cell_name A_productive A_unproductive B_productive B_unproductive clonal_group group_size
P01-PP10A2-T3-S1-Sc_S98_L00_al TRAV12-2_CCGTGGGTGGGA_TRAJ7 1 59
P01-PP10A4-T4-S2-Sc_S100_L00_a TRAV12-2_GTGAAGGGAGGAAA_TRAJ47 TRBV4-1_GCCAATGGGGACAAGATA_TRBJ2-3 4 14
P01-PP10A5-T4-S2-Sc_S101_L00_a TRAV12-2_TGAACGGAGACAAC_TRAJ21 TRBV2_AGCAGCCCCCCGGGGGAGCA_TRBJ2-7
P01-PP10A6-T4-S2-Sc_S102_L00_a TRAV12-2_GCCGTATCAGG_TRAJ45 TRBV4-1_CAGCCGTGCGGTCAGCGATAC_TRBJ2-3 13 5
It looks that these are singletons! right?
Yes, exactly. If these entries are blank then that cell doesn't have any apparent clonal relationships and is a singleton.
thanks
Hi Hashem,
This issue is currently empty! Happy to help if you can add a bit more context :)
Mike