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TencentAILabHealthcare / scPROTEIN

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protein level #1

Closed madrox22 closed 10 months ago

madrox22 commented 1 year ago

Hi,

How do we go from the "peptide uncertainty" to protein level after running scPROTEIN?

Thanks.

nkuweili commented 1 year ago

Hi, @madrox22

After generating the peptide uncertainty with stage1, you can then use the function load_sc_proteomic_features to obtain the protein-level data (also can see our tutorial for stage1: https://github.com/TencentAILabHealthcare/scPROTEIN/blob/main/tutorial_scPROTEIN_stage1.ipynb ). It takes peptide uncertainty and peptide data as input and outputs the protein-level data by uncertainty-guided aggregation.