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The-Sequence-Ontology / SO-Ontologies

Collect of SO Ontologies
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LAMHDI SO review ticket #2: ‘gene’ #321

Open srynobio opened 9 years ago

srynobio commented 9 years ago

The current definition of ‘gene’ is “a sequence region (or regions) that includes all of the sequence elements necessary to encode a functional transcript. A gene may include regulatory regions, transcribed regions and/or other functional sequence regions.” Consider the following minor change: "A region (or regions) that include all of the sequence elements facilitating the production of a functional transcript when encoded in the genome of some cell or virion. A gene may include sequence encoded in regulatory regions, transcribed regions and/or other functional sequence regions." This change, or some similar revision, would address the fact that all regions of a gene do not truly ‘encode’ the transcript derived from it, and that many parts of a gene (such as some enhancer regions) may not even be ‘necessary’ - ie it might only regulate or increase transcription.

srynobio commented 9 years ago

Response from @keilbeck

Hi Matt Since we got the travel grant to work with you on these issues, I am making all the lamdhi requests 'pending' --K