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The-Sequence-Ontology / SO-Ontologies

Collect of SO Ontologies
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sncRNA term request #485

Closed murphyte closed 4 years ago

murphyte commented 4 years ago

name: Small non-coding RNA term: sncRNA definition: A non-coding RNA <200 nucleotides in length parent: ncRNA children: miRNA, siRNA, piRNA, snoRNA, snRNA, tRNA paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046292/

The sncRNA term is older than that publication, but I didn't go looking for who first coined it.

In addition, the definition for lncRNA should be revised to be "greater than or equal to 200 nt in length"

srengel commented 4 years ago

searching in textpressocentral.org for 'sncRNA' finds this 2007 paper as earliest mention:

https://www.ncbi.nlm.nih.gov/pubmed/17949481

davidwsant commented 4 years ago

I think we have an equivalent term, small_regulatory_ncRNA (SO:0000370). I think that adding a synonym of sncRNA would be sufficient, as the definition lines up. The current definition is "A non-coding RNA less than 200 nucleotides long, usually with a specific secondary structure, that acts to regulate gene expression. These include short ncRNAs such as piRNA, miRNA and siRNAs (among others)". Does that sound sufficient?

murphyte commented 4 years ago

sncRNA would be a parent of small_regulatory_ncRNA. It includes those, but doesn't require regulatory function.

davidwsant commented 4 years ago

Hi Terrence,

I have updated the SO with the new information. The new term info is as follows:

id: SO:0002247 name: sncRNA def: "A non-coding RNA less than 200 nucleotides in length."

The SO Browser should be updated with the changes within about 24 hours.

Thanks,

Dave Sant