In my opinion, informations such as number_of_animals, strain or sex should not be part of this message. Rather, things like this should be part of the ExperimentalCohort element, which should be able to contain multiple CohortMeasurement instances. However, the ExperimentalCohort element has so far only been declared, but not defined. It would probably also be more flexible if lists were used for strain and sex, so that the element ExperimentalCohort can also be applied to mixed cohorts.
It is also not clear from the message what, when, how and where was measured. There is only the field assay, which is also undefined so far. In MPD, such information can be found in more or less unstructured form using the ID measnum.
The field standard_error_of_mean is redundant because it can be calculated from the fields standard_deviation and number_of_animals. Furthermore, in this context, a Z-score makes no sense to me. As I understand it, a Z-score indicates by how many standard deviations an observed value deviates from the mean. To which observed value does this Z-score refer here?
So far there is only a rudimentary definition of a message for measurements of cohorts that looks as follows:
In my opinion, informations such as
number_of_animals
,strain
orsex
should not be part of this message. Rather, things like this should be part of theExperimentalCohort
element, which should be able to contain multipleCohortMeasurement
instances. However, theExperimentalCohort
element has so far only been declared, but not defined. It would probably also be more flexible if lists were used forstrain
andsex
, so that the elementExperimentalCohort
can also be applied to mixed cohorts.It is also not clear from the message what, when, how and where was measured. There is only the field
assay
, which is also undefined so far. In MPD, such information can be found in more or less unstructured form using the IDmeasnum
.The field
standard_error_of_mean
is redundant because it can be calculated from the fieldsstandard_deviation
andnumber_of_animals
. Furthermore, in this context, a Z-score makes no sense to me. As I understand it, a Z-score indicates by how many standard deviations an observed value deviates from the mean. To which observed value does this Z-score refer here?