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TheSatoLab / Merbecovirus_recombination

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how to define the breakpoints with CI? #6

Closed liamxg closed 6 months ago

liamxg commented 6 months ago

Dear @JetVirology22,

I find that the breakpoints in Fig. 2A with red color are different from SuppleTable 2, the breakpoints have 99% CI, I am confused, could you please help me out, thanks.

JetVirology22 commented 6 months ago

@liamxg , You are right. The breakpoints were identified in the RDP5, and the imported data is a sequence aligned. Once we get the breakpoints in RDP5, we patterned these on the original position in the GenBank. See TableS3. The CI from these breakpoints were given in the RDP5 result.

liamxg commented 6 months ago

Dear @JetVirology22, Got it. TableS1 is based on alignment, TableS3 is based on HCoV-EMC-2012 (NC_019843.3), right?

JetVirology22 commented 6 months ago

@liamxg , Yes, you are correct!

liamxg commented 6 months ago

cool!