This is a correction of normalized_counts of genes from limma-voom.
Initially, it returned the log(cpm): v$E
Now it return cpm: 2^v$E
I think it's more relevant,
and this correction is necessary to run Switch in Dekupl-annot:
Switch makes log(normalized_count).
If normalized_counts = log(cpm), it could be <0
so log(normalized_count) = log(<0) and return an error.
jaudoux
commented
5 years ago
This is a correction of normalized_counts of genes from limma-voom. Initially, it returned the log(cpm): v$E Now it return cpm: 2^v$E
I think it's more relevant, and this correction is necessary to run Switch in Dekupl-annot: Switch makes log(normalized_count). If normalized_counts = log(cpm), it could be <0 so log(normalized_count) = log(<0) and return an error.