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4mmc + LSD #60

Open utaninja opened 9 months ago

utaninja commented 9 months ago

4mmc + LSD Caution

The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops, in addition to the possible negative side effects of coming down from said stimulant while on a psychedelic. In extreme cases, stimulants, especially in combination can result in severe vasoconstriction, tachycardia, hypertension, and heart failure. (open to this sentence getting adjusted)

These sources show 4mmc is a stimulant- 4mmc is a stimulant- https://jpet.aspetjournals.org/content/339/2/530 https://pubmed.ncbi.nlm.nih.gov/22169943/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504998/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246659/ https://pubmed.ncbi.nlm.nih.gov/24795175/

Sources for the claim LSD is a stimulant/heart concerns- https://pubmed.ncbi.nlm.nih.gov/25575620/ https://pubmed.ncbi.nlm.nih.gov/31733631/

Stimulants have concerns of severe vasoconstriction, tachycardia, hypertension, and heart failure. https://pubmed.ncbi.nlm.nih.gov/19948186/#:~:text=They%20include%20amphetamine%20and%20its,their%20use%20as%20nasal%20decongestants. https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15465 https://accp1.onlinelibrary.wiley.com/doi/full/10.1002/jcph.1918 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10510945/#:~:text=Amphetamine%2Dinduced%20heart%20failure%20typically,including%20echocardiography%20and%20cardiac%20biomarkers.

I'm struggling to find sources to show that stimulants cause/raise anxiety. I also would appreciate if someone could read through all of this before this being pushed to the database. I feel relatively confident when it comes to the caution but uncertain that the sources demonstrate this.

LunaUrsa commented 7 months ago

Need to verify this