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Tsjerk / Insane

INSert membrANE - A simple, versatile tool for building coarse-grained simulation systems
GNU General Public License v2.0
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Specifying lipid ratio in outer and inner leaflet #80

Closed kong1-731 closed 1 year ago

kong1-731 commented 1 year ago

I am just wondering if it is possible to embed a protein in a membrane and to specify the lipid ratio in the outer and inner leaflets separately rather than just the ratio overall in order to design outer and inner leaflets with different lipid compositions. I couldn't find a clear example of this. Thank you for any guidance!

Tsjerk commented 1 year ago

This is what insane was designed for from the onset. You can use -l and -u to specify lipids for the lower and upper leaflets, respectively. If only -l is used, then it is interpreted as specifying both leaflets. Examples are given in the original paper.