UCL / TLOmodel

Epidemiology modelling framework for the Thanzi la Onse project
https://www.tlomodel.org/
MIT License
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Collection of parameters that specify "full" adherence to clinical guidance #865

Closed tbhallett closed 1 year ago

tbhallett commented 1 year ago

I would like to record all the parameters (and their values) in the model that reflect "full adherence" to clinical guidance. i.e. all referrals happen, the probability of every test is 1.0, etc.

A lot of these things have been manipulated by @BinglingICL as she has calibrated the model to the available data on activity in the HealthCare system --- so those are the starting point. But, there may be others, and I would like to ask @BinglingICL if she can, following the calibration work, liaise with the modelling team to collect these all up!

BinglingICL commented 1 year ago

Hi @tbhallett, thanks very much for raising this issue.

To start with, I will make a list of the parameters/changes I have updated.made when calibrating/tuning the appointment usage compared to observed/DHIS2 data.

Then let us make a full list to incorporate all relevant parameters.

BinglingICL commented 1 year ago

With this parameter list collected and coded into "fullmodel", we will do overall calibrations for our model and compare the healthcare system usage with (e.g. parameters with reduced values) and without the calibrations (e.g. parameters with default values, or 1.0).

Together with Issue #822 fixed (and maybe Issue #879), we will have the results figures ready to be added to our m/s on healthcare workforce : )

BinglingICL commented 1 year ago

To start with, I will make a list of the parameters/changes I have updated.made when calibrating/tuning the appointment usage compared to observed/DHIS2 data.

This link summarised the parameters/changes I have made/updated by now: https://docs.google.com/spreadsheets/d/1r6V5XofdWoW70AYllqx7ADYnHAePgkx6v53bur2Ds30/edit#gid=1858302919.

BinglingICL commented 1 year ago

Hi Joe @joehcollins, here is the issue : )

BinglingICL commented 1 year ago

To start with, I will make a list of the parameters/changes I have updated.made when calibrating/tuning the appointment usage compared to observed/DHIS2 data.

This link summarised the parameters/changes I have made/updated by now: https://docs.google.com/spreadsheets/d/1r6V5XofdWoW70AYllqx7ADYnHAePgkx6v53bur2Ds30/edit#gid=1858302919.

The hsi-calibrated parameter collection is now 99% done and the 1% is about the possible parameters/changes re. malaria/opd and ANC/IPAadmission. Next, we are going to collect all relevant parameters specifying full adherence to clinical guidance, by looking into various modules of diseases, health care seeking, etc. The link is https://docs.google.com/spreadsheets/d/1zUm1LAAcbeS0lT9SgGtlapfk3n6WyOWN6aScivcU3Fw/edit#gid=0

joehcollins commented 1 year ago

@BinglingICL - just to say I havent forgotten about this and will make I add to this list when I'm back from Cape Town next week!

joehcollins commented 1 year ago

Also just to ask - assume this list will not include parameters relating to test sensitivity/specificity?

BinglingICL commented 1 year ago

@BinglingICL - just to say I havent forgotten about this and will make I add to this list when I'm back from Cape Town next week!

Thanks Joe @joehcollins. No worries at all. I am on to it this week and will send to you and Tim and others for review. Enjoy the trip!

BinglingICL commented 1 year ago

Also just to ask - assume this list will not include parameters relating to test sensitivity/specificity?

Good question. I will try to include them, too. Then let's decide how to use (or drop) it when do the simulation and analysis.

BinglingICL commented 1 year ago

Todo: (1) seek team's advice on confirming the parameters list and default values: https://docs.google.com/spreadsheets/d/1zUm1LAAcbeS0lT9SgGtlapfk3n6WyOWN6aScivcU3Fw/edit#gid=0 (2) write a function to allow switching parameters to the default values, i.e., full adherence to clinical guidance/etc; see branch #973

Relevant questions to think about: (1) what does "full adherence to clinical guidance" exactly mean? (2) in current tlo model, such parameters do not exist in each module (such as cancer, rti); is this a potential issue as we may not fully represent the adherence to clinical guidance across different diseases/services? (3) where to implement this function in a scenario? draw_parameters? fullmodel function?