USEPA / CompTox-ToxCast-tcplFit2

Performs basic concentration response curve fitting
https://cran.r-project.org/package=tcplfit2
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Add further descriptions about model parameters in documentation #16

Open sedavid01 opened 10 months ago

sedavid01 commented 10 months ago

All of the models available in tcplfit2 have brief information about the parameters, but some of the descriptions are common across model documentation though may have slightly different interpretations given the model of interest.

Needs:

sedavid01 commented 10 months ago
  1. Make a list of parameters in available tcplfit2 models.
  2. Obtain current descriptions of model parameters (for example, gain and loss parameters with relation to AC50)
  3. Draft description of models and how they impact/relate to the model shape.
  4. Set-up meeting with SME's - Katie, Kelly, Logan, Richard, and Sarah. (Look out the next 2-3 weeks for best availability for all individuals.)
sedavid01 commented 9 months ago

From discussion with the SME's and main users of tcplfit2, path forward:

sedavid01 commented 9 months ago

From our discussion this morning, ensure that when you are developing this vignette it is a "stand-alone" vignette that users can open and read. That is, provides a single module of how the various model parameters impact curve shapes.

Focus on just the continuous models for now. Once the dichotomous models are pulled into the package then we can update this vignette.