I have a cyclic peptide sequence. I put it into Alphafold2 Colab, but I didn't get a cyclic peptide structure. What should I do to connect the C-terminal and N-terminal for the next dynamic simulation (GROMACS)?
Should I do some processing on the structure obtained by Alphafold2 Colab for Gromacs dynamics? Or input sequence to Alphafold2 Colab need for some pre-processing? Or can Alphafold2 not predict the sequence of cyclic peptides?
It's really important for my research, thanks for any help.
I have a cyclic peptide sequence. I put it into Alphafold2 Colab, but I didn't get a cyclic peptide structure. What should I do to connect the C-terminal and N-terminal for the next dynamic simulation (GROMACS)?
Should I do some processing on the structure obtained by Alphafold2 Colab for Gromacs dynamics? Or input sequence to Alphafold2 Colab need for some pre-processing? Or can Alphafold2 not predict the sequence of cyclic peptides?
It's really important for my research, thanks for any help.