VirtualMetabolicHuman / AGORA

The aim of this repository is to maintain, refine, and expand the AGORA collection of genome-scale metabolic reconstructions for human gut microbes through the use of issues. Please note that pull requests will be automatically closed.
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Flux Variability Analysis min-max mix up in Bifidobacterium_longum_infantis_ATCC_15697 #7

Closed shraddhakhirwadkar closed 3 years ago

shraddhakhirwadkar commented 3 years ago

Hi! I have been trying to simulate individual strains, Bifidobacterium longum infantis ATCC 15697 in this case, in BacArena and looking at the flux variability during the simulation with fluxVarSim(). The only media that is in the environment is 10% of essential media and 1mM glc_D. I have attached an image of the results, and the FVA seems to have a mix up between min-max. Does anyone know why this happens? Please let me know if I need to provide any clarification. FVA

EX_for(e) 991.4599 0.0000 EX_fru(e) 0.0000 0.0000 EX_fuc_L(e) 0.0000 0.0000 EX_gal(e) 0.0000 0.0000 EX_gcald(e) 0.0000 0.0000 EX_gchola(e) 0.0000 0.0000 EX_glc_D(e) 0.0000 -610.0665 Thank you for your help!

shraddhakhirwadkar commented 3 years ago

https://github.com/euba/BacArena/issues/172