If I want to incorporate doubelt detection in my scRNA-seq workflow, should I perform imputation before or after detecting and removing doublets? A second question is if I need to integrate multiple datasets, can I still perform imputation on individual dataset and use the imputed output as input for integration? Thanks!
If I want to incorporate doubelt detection in my scRNA-seq workflow, should I perform imputation before or after detecting and removing doublets? A second question is if I need to integrate multiple datasets, can I still perform imputation on individual dataset and use the imputed output as input for integration? Thanks!