WGLab / CancerVar

Clinical interpretation of somatic mutations in cancer
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Question about CBP10 in CancerVar web server. #13

Open lincj1994 opened 3 years ago

lincj1994 commented 3 years ago

Hi, in CancerVar web server, CBP10 was "Predictive Mostly damaging: SIFT, PolyPhen2, MutationAssessor, MetaSVM, MetaLR, FATHMM, GERP++_RS". The word "mostly" was very ambiguous. I dont know many deleterious predictions will be assigned 1 (Supporting) or 2 (Strong)?

quanliustc commented 3 years ago

For CBP10 if the variant has been predicted as damage in >=3 methods, will be given 1, if be predicted in >=5 methods as damage, will be given 2.