search

WGLab / DeepMod2

DNA 5mC methylation detection from Dorado or Guppy basecalled Oxford Nanopore reads
MIT License
36 stars 2 forks source link

detect unknown modifications #12

Open gerbenm opened 1 year ago

gerbenm commented 1 year ago

Hi, Would DeepMod2 be able to pinpoint locations where uncharacterised modifications are present? The current base callers can not handle this, because not trained for these. But being able to localise where unknown modifications are present would already be very helpfull. Thanks a ton, Gerben

umahsn commented 1 year ago

Hi,

Currently we have not developed any models for de-novo modification detection, but it is something we plan to do in the near future. We will update the issue once we have such models.

Best, Umair