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WGLab / NanoMod

NanoMod: a computational tool to detect DNA modifications using Nanopore long-read sequencing data
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Preparing genomes for sequencing? #24

Open starkeynight opened 1 year ago

starkeynight commented 1 year ago

Are there any recommended methods to obtain non-modified samples for sequencing (e.g. whole-genome amplification, or something else?)?

liuqianhn commented 1 year ago

whole-genome amplification and PCR before sequencing will remove the existence of modified bases.