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WGLab / doc-ANNOVAR

Documentation for the ANNOVAR software
http://annovar.openbioinformatics.org
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one locus match two different transcripts of the same gene #253

Open yanwuanxin opened 2 months ago

yanwuanxin commented 2 months ago
415c21d20af932d353a35ff09c31b23

one locus match two different transcripts of the same gene, how to interpret this?

kaichop commented 1 month ago

This is called "alternative splicing". Each gene can have multiple transcripts with different combinations of exons.

On Wed, Sep 4, 2024 at 3:42 AM yanwuanxin @.***> wrote:

415c21d20af932d353a35ff09c31b23.png (view on web) https://github.com/user-attachments/assets/ccca51f3-aed0-45c9-8c56-c7723ca40b49 one locus match two different transcripts of the same gene, how to interpret this?

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yanwuanxin commented 1 month ago

hi, based on the above question, is there a way to keep only the most commonly used transcript when annotate

yanwuanxin commented 1 month ago

to keep only the most commonly used transcript in anot, use MANE Select