Given association result file doesn't contain any Amino Acid markers. Please check it again.

[pcibin]

Hello,

I am analysing my data using HATK. Evertything seems to work nice, but when I look at the Manhattan plot, I only see "light grey squares" (so, intergenic dbSNP markers) and I don't get the heatmap, as there are no amino acid markers. I have also tried to implement each module separately, but it didn't change anything. I have also tried to use different imgt version, but I got the same error. I have done the HLA imputation using CookHLA but I didn't get any error. What did I do wrong? I apologize for any mistake on my side, it's the first time I work on anything like this!

#######

python3 HATK.py \ --variants /variants/NMA3-HNR-SHIP_v4_c6_29-34Mb \ --hped /CookHLA_results/NMA3-HNR-SHIP_HLA_IMPUTATION.MHC.HLA_IMPUTATION_OUT.hped \ --2field \ --pheno /pheno/pheno_EN.phe \ --pheno-name EN \ --out NMA3_EN/RESULT_hatk.EN_peanut.chr6.hg18 \ --imgt 3440 \ --hg 18 \ --imgt-dir /IMGTHLA3440 \ --multiprocess 2

[ProcessIMGT.py]: Generating sequence information dictionary for HLA A.

[ProcessIMGT.py]: Generating sequence information dictionary for HLA B.

[ProcessIMGT.py]: Generating sequence information dictionary for HLA C.

[ProcessIMGT.py]: Generating sequence information dictionary for HLA DPA1.

[ProcessIMGT.py]: Generating sequence information dictionary for HLA DPB1.

[ProcessIMGT.py]: Generating sequence information dictionary for HLA DQA1.

[ProcessIMGT.py]: Generating sequence information dictionary for HLA DQB1.

[ProcessIMGT.py]: Generating sequence information dictionary for HLA DRB1.

[HLA_Study.py]: IMGT2Seq result : < IMGT2Sequence(Newly generated.) >

• HLA Amino Acids : NMA3_EN/HLA_DICTIONARY_AA.hg18.imgt3440
• HLA SNPs : NNMA3_EN/HLA_DICTIONARY_SNPS.hg18.imgt3440
• HLA Allele Table : NMA3_EN/HLA_ALLELE_TABLE.imgt3440.hat
• Maptables for heatmap : A : NNMA3_EN/HLA_MAPTABLE_A.hg18.imgt3440.txt B : NMA3_EN/HLA_MAPTABLE_B.hg18.imgt3440.txt C : NMA3_EN/HLA_MAPTABLE_C.hg18.imgt3440.txt DPA1: NMA3_EN/HLA_MAPTABLE_DPA1.hg18.imgt3440.txt DPB1: NMA3_EN/HLA_MAPTABLE_DPB1.hg18.imgt3440.txt DQA1: NMA3_EN/HLA_MAPTABLE_DQA1.hg18.imgt3440.txt DQB1: NMA3_EN/HLA_MAPTABLE_DQB1.hg18.imgt3440.txt DRB1: NMA3_EN/HLA_MAPTABLE_DRB1.hg18.imgt3440.txt

[HLA_Study.py]: Given HPED file('/CookHLA_results/NMA3-HNR-SHIP_HLA_IMPUTATION.MHC.HLA_IMPUTATION_OUT.hped') is to be processed by NomenCleaner.

[NomenCleaner.py]: Generating CHPED with Maximum 2 fields HLA alleles.

[bMarkerGenerator.py]: Making Reference Panel for "NMA3_EN/RESULT_hatk.EN_peanut.chr6.hg18"

[1] Generating Amino acid(AA)sequences from HLA types. [2] Encoding Amino acids positions. [3] Encoding HLA alleles. [4] Generating DNA(SNPS) sequences from HLA types. [5] Encoding SNP positions. [6] Extracting founders. [7] Merging SNP, HLA, and amino acid datasets. Warning: Variants 'HLA_A01:02' and 'HLA_A01:01' have the same position. Warning: Variants 'HLA_A02:01' and 'HLA_A01:02' have the same position. Warning: Variants 'HLA_A02:05' and 'HLA_A02:01' have the same position. 2745 more same-position warnings: see log file. [8] Performing quality control. [9] Making reference panel for HLA-AA,SNPS,HLA and Normal variants(SNPs) is Done!

[HLA_Study.py]: bMarkerGenerator result(Prefix) : NMA3_EN/RESULT_hatk.EN_peanut.chr6.hg18

[HLA_Study.py]: Logistic Regression result : NMA3_EN/RESULT_hatk.EN_peanut.chr6.hg18.assoc.logistic

[HLA_Study.py]: Manhattan result : NMA3_EN/RESULT_hatk.EN_peanut.chr6.hg18.manhattan.pdf

[heatmap.py::ERROR]: Given association result file(EN/RESULT_hatk.EN_peanut.chr6.hg18.assoc.logistic) doesn't contain any Amino Acid markers. Please check it again.

[HLA_Study.py::WARNING]: Failed to plot Heatmap of HLA A gene.

[heatmap.py::ERROR]: Given association result file(EN/RESULT_hatk.EN_peanut.chr6.hg18.assoc.logistic) doesn't contain any Amino Acid markers. Please check it again.

[HLA_Study.py::WARNING]: Failed to plot Heatmap of HLA B gene.

[heatmap.py::ERROR]: Given association result file(EN/RESULT_hatk.EN_peanut.chr6.hg18.assoc.logistic) doesn't contain any Amino Acid markers. Please check it again.

[HLA_Study.py::WARNING]: Failed to plot Heatmap of HLA C gene.

[heatmap.py::ERROR]: Given association result file(EN/RESULT_hatk.EN_peanut.chr6.hg18.assoc.logistic) doesn't contain any Amino Acid markers. Please check it again.

[HLA_Study.py::WARNING]: Failed to plot Heatmap of HLA DPA1 gene.

[heatmap.py::ERROR]: Given association result file(EN/RESULT_hatk.EN_peanut.chr6.hg18.assoc.logistic) doesn't contain any Amino Acid markers. Please check it again.

[HLA_Study.py::WARNING]: Failed to plot Heatmap of HLA DPB1 gene.

[heatmap.py::ERROR]: Given association result file(EN/RESULT_hatk.EN_peanut.chr6.hg18.assoc.logistic) doesn't contain any Amino Acid markers. Please check it again.

[HLA_Study.py::WARNING]: Failed to plot Heatmap of HLA DQA1 gene.

[heatmap.py::ERROR]: Given association result file(EN/RESULT_hatk.EN_peanut.chr6.hg18.assoc.logistic) doesn't contain any Amino Acid markers. Please check it again.

[HLA_Study.py::WARNING]: Failed to plot Heatmap of HLA DQB1 gene.

[heatmap.py::ERROR]: Given association result file(EN/RESULT_hatk.EN_peanut.chr6.hg18.assoc.logistic) doesn't contain any Amino Acid markers. Please check it again.

[HLA_Study.py::WARNING]: Failed to plot Heatmap of HLA DRB1 gene.

[HLA_Study.py]: Heatmap result : A : -1 B : -1 C : -1 DPA1 : -1 DPB1 : -1 DQA1 : -1 DQB1 : -1 DRB1 : -1

[WansonChoi]

@pcibin

Hi, Thank you for your interest in HATK.

It seems the bMarkerGenerator failed to add HLA related markers with the outputs from the IMGT2Seq and NomenCleaner.

Could you show the 1st 10 ~ 20 lines of

(1) NMA3_EN/HLA_DICTIONARY_AA.hg18.imgt3440.txt (2) NNMA3_EN/HLA_DICTIONARY_SNPS.hg18.imgt3440.txt (3) the 2-field CHPED file generated from the NomenCleaner (maybe 'NMA3_EN/*.imgt3440.2field.chped')

those files?

Anonymize sample labels in the (3) if necessary.

(+ Is the output directory 'NMA3_EN/'? There are 'NNMA3_EN/' and 'EN/' used for the output directory in your message. Are they typos?)

[pcibin]

@WansonChoi Thank you for your fast reply!

1) NMA3_EN/HLA_DICTIONARY_AA.hg18.imgt3440.txt

A01:01 MAVMAPRTLLLLLSGALALzTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQKMEPRAPWIEQEGPEYWDQETRNMKAHSQTDRANLGTLRGYYNQSEDGSHTIQIMYGCDVGPDGRFLRGYzRQDAYDGKDYzIALNEDLRSWTAADMAAQITKRKWEAVHAAEzQRRVYLEGRCVDGLRRYLENzGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDzQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVSLTACKV A01:02 MAVMAPRTLLLLLSGALALzTQTWAGSHSMRYFSTSVSRPGSGEPRFIAVGYVDDTQFVRFDSDAASQKMEPRAPWIEQEGPEYWDQETRNMKAHSQTDRANLGTLRGYYNQSEDGSHTIQIMYGCDVGPDGRFLRGYzRQDAYDGKDYzIALNEDLRSWTAADMAAQITKRKWEAVHAAEzQRRVYLEGRCVDGLRRYLENzGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDzQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVSLTACKV A01:03 MAVMAPRTLLLLLSGALALzTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQKMEPRAPWIEQEGPEYWDQETRNMKAHSQTDRANLGTLRGYYNQSEDGSHTIQMMYGCDVGPDGRFLRGYzRQDAYDGKDYzIALNEDLRSWTAADMAAQITKRKWEAVHAAEzQRRVYLEGRCVDGLRRYLENzGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDzQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVSLTACKV A01:04 MAVMAPRTLLLLLSGALALzTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQKMEPRAPWIEQEGPEYWDQETRNMKAHSQTDRANLGTLRGYYNQSEDGSHTIQIMYGCDVGPDGRFLRGYzRQDAYDGKDYzIALNEDLRSWTAADMAAQITKRKWEAVHAAEzQRRVYLEGRCVDGLRRYLENzGKETLQRTDPPQDTYDPPPHLXxxxxxxxxxxxxxxxxxxxxxxxxxxxzxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx A01:06 MAVMAPRTLLLLLSGALALzTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQKMEPRAPWIEQEGPEYWDQETRNMKAHSQTDRANLGTLRGYYNQSEDGSHTIQIMYGCDVGPDGRFLRGYzRQDAYDGKDYzIALNEDLRSWTAADMAAQITKRKWEAVHAAEzQLRAYLEGRCVDGLRRYLENzGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDzQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVSLTACKV A01:07 xxxxxxxxxxxxxxxxxxxzxxxxxxSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQKMEPRAPWIEQERPEYWDQETRNVKAHSQTDRENLGTLRGYYNQSEAGSHTIQIMYGCDVGPDGRFLRGYzRQDAYDGKDYzIALNEDLRSWTAADMAAQITKRKWEAVHAAEzQRRVYLEGRCVDGLRRYLENzGKETLQRTxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxzxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx A01:08 xxxxxxxxxxxxxxxxxxxzxxxxxxSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQKMEPRAPWIEQEGPEYWDQETRNMKAHSQTDRANLGTLRGYYNQSEDGSHTIQIMYGCDVGPDGRFLRGYzRQDAYDGKDYzIALNEDLRSWTAADMAAQITKRKWEAVHAAEzQRRVYLEGWCVDGLRRYLENzGKETLQRTxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxzxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx A01:09 MAVMAPRTLLLLLSGALALzTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQLVRFDSDAASQKMEPRAPWIEQEGPEYWDQETRNMKAHSQTDRANLGTLRGYYNQSEDGSHTIQIMYGCDVGPDGRFLRGYzRQDAYDGKDYzIALNEDLRSWTAADMAAQITKRKWEAVHAAEzQRRVYLEGRCVDGLRRYLENzGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDzQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVSLTACKV A01:10 xxxxxxxxxxxxxxxxxxxzxxxxxxSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQKMEPRAPWIEQEGPEYWDQETRNMKAHSQTDRANLGTLRGYYNQSEDGSHTIQIMYGCDVGPDGRFLRGYzRQDAYDGKDYzIALNEDLRSWTAADMAAQITKRKWEAARRAEzQRRVYLEGRCVDGLRRYLENzGKETLQRTxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxzxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx A01:11N MAVMAPRTLLLLLSGALALzTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQKMEPRAPWIEQEGPEYWDQETRNMKAHSQTDRANLGTLRGYYNQSEDGSHTIQIMYGCDVGPDGRFLRGYzRQDAYDGKDYzIALNEDLRSWTAADMAAQITKRKWEAVHAAEzQRRVYLEGRCVDGLRRYLENz........DPPKTHMTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDzQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWELSSQPTIPIVGIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSDVSLTACKV

2) NNMA3_EN/HLA_DICTIONARY_SNPS.hg18.imgt3440.txt

A01:01 ATGGCCGTCATGGCGCCCCGAACCCTCCTCCTGCTACTCTCGGGGGCCCTGGCCCTzGACCCAGACCTGGGCGGzGTGAGTGCGGGGTCGGGAGGGAAACCGCCTCTGCGGGGAGAAGCAAGGGGCCCTCCTGGCGGGGGCGCAGGACCGGGGGAGCCGCGCCGGGAGGAGGGTCGGGCAGGTCTCAGCCACTGCTCGCCCCCAGGCTCCCzACTCCATGAGGTATTTCTTCACATCCGTGTCCCGGCCCGGCCGCGGGGAzGCCzCCGCTTCATCGCCGTGGGCzTACGTGGACGzACACGzCAGTTCGTGCGGTTCGACAGCGACGCCGCGAGCCAGAAGATGGAGCCGzCGGGCGCCGTGGATAGAGCAGGAGGGGCCGGAGTATTGGGACCAGGzAGACACGGAzATATGAAGGCCCACTCACAGACTGACCGAGCGAACCTGGGGACCCTGCGCGGCTACTACAACCAGAGCGAGGACGGTGAGTGACCCCGGCCCGGGGzCGCAGGTCACGACCzCCTCATCCCCCzACGGACGGGCCAGGTCGCCCACAGTCTCCGGGTCCGAGATCCACCCCGAAGCCGCGGGACTCCGAGACCCTTGTCCCGGGAGAGGCCCAGGCGCCTTTACzCCGGTTTCATTTTCAGTTTAGGCCAAAAAzTCCCCCCzGGGTTGGTCGGGGCGGGGCGGGGCzTCGGGGGACzTGGGCTGACCGCGGGGTCGGGGCCAGGTTCTCACACCzATCCAGATAATGTATGGCTGCGACGTGGGGCCGGzACGGGCGCTTCCTCCGCGGGTACCGGCAzGGACGCCTACGACGGCAAGGATTAzCATCGCCCTGAzACzGAGGACCTGCGCTCTTGGACCGCGzGCGGACATGGCAGzCTCAGATCACCAAGCGCzAAGTzGGGAGzGCGGTCCAzTGCGGCzGGAGCAGCGGAGAGTCTACCTGGAGGGCCGGzTGCGTGzGACGGGCTCCGCzAGATAzCCTGGAGAACGGGAAGGAGACGCTGCAGCzGCACGGGTACCAGGGGCCACGGGGCGzCCTCCCTGATCGCCTzATzAGATCTCCCGGGCTGGCCTCzCCACAAGGAGGGGAGACAATTGGGACCAACACTAGAATATCACCCTCCCTCTzGGTCCTGAGGGAGAGGAATCCTCCTGGGTTTCCAGATCCTGTACCAGAGAGTGACTCTGAGGTTCCGCCCTGCTCTCTGACACAATTAAGGGATAAAAzTCTCTGAAGGAGTGACGGGAAGACGATCCCTCGAzATACTGATGAGTGGTTCCCTTTGACACzCGGCAGCAGCCTTGGGCCCGTGACTTTTCCTCTCAGGCCTTGTTCTCTGCTTCACACTCAATGTGTGTGzGGGGzTCTGAGTCCAGCACTTCTGAGTCTCTCAGCCTCCACTCAGGTCAGGACCAGAAGTCGCTGTTCCCTTCTCzAGGGAzATAGAAGATTATCCCAGGTGCCTGTGTCCAGGCTGGTGTCTGGGTTCTGTGCTCTCTTCCCCATCCCGGGTGTCCTGTCCATTCTCAAGATGGCCACAzTGCGTGCTGGTGGAGTGTCCCATGACAGATGCAAAATGCCTGAATTTTzCTGACTCTTCCCGTCAGACCCCCCCzAAGACACATATGACCCACCACCCCATCTCTGACCATGAGGCCACCCTGAGGTGCTGGGCCCTGGGCTTCTACCCTGCGGAGATCACACTGACCTGGCAGCGGGATGGGGAGGACzCAGACCCAGGACACGGAGCTCGTGGAGACCAGGCCTGCzAGGGGATGGAACCTTCCAGAAGTGGGCGGCTGTGGTGGTGCCTTCTGGAGAGGAGCAGAGATACACCTGCCATGTGCAGCATGAGGGTCTGCCCAAGCCCCTCACCCTGAGATGGGGTAAGGAGGGAGATGGGGGTGTCATGTCTCTTAGGGAAAGCzAGGAGCCTCTCTGGAGACCTTTAGCAGGGTCAGGGCCzCCTCACCTTCCCCTCTTTTCCCAGAGCTGTCTTCCCAGCCCACCATCCCCATCGTGGGCATCATTGCTGGCCTGGTTCTCCTTGGAGCTGTGATCACTGGAGCTGTGGTCGCTGCCGTGATGTGGAGGAGGAAGAGCTCAGGTGGAGzAAGGGGTGAAGGGTGGGGTCTGAGATTTCTTGTCTCACTGAGGGTTCCAAGCCCCAGCTAGAAATGTGCCCTGTCTCATTACTGGGAAGCACCTTCCACAATCATGGGCCGACCCAGCCTGGGCCCTGTGTGCCAGCACTTACTCTTTTGTAAAGCACCTGTTAAAATGAAGGACAGATTTATCACCTTGATTACGGCGGTGATGGGACCTGATCCCAGCAGTCACAAGTCACAGGGGAAGGTCCCTGAGGACAGACCTCAGGAGGGCTATTGGTCCAGGACCCACACCTGCTTTCTTCATGTTTCCTGATCCCGCCCTGGGTCTGCAGTCACACATTTCTGGAAACTTCTCTGGGGTCCAAGACTAGGAGGTTCCTCTAGGACCTTAAGGCCCTGGCTCCTTTCTGGTATCTCACAGGACATTTTCTTCCCACAGATAGAAAAGGAGGGAGTTACACTCAGGCTGCAAGTAAGTATGAAGGAGGCTGATGCCTGAGGTCCTTGGGATATTGTGTTTGGGzAGCCCATGGGGGAGCTCACCCACCCCACAATTCCTCCTCTAGCCACATCTTCTGTGGGATCTGACCAGGTTCTGTTTTTGTTCTACCCCAGGCAGTGACAGTGCCCAGGGCTCTGATGTGTCTCTCACAGCTTGTAAAGGTGAGAGCTTGGAGGGCCTGATGTGTGTTGGGTGTTGGGTGGAACAGTGGACACAGCTGTGCTATGGGGTTTCTTTGCGTTGGATGTATTGAGCATGCGATGGGCTGTTTAAGGTGTGAzCCCCTCACTGTGATGGATATGAATTTGTTCATGAATATTTTTTTCTATAGTGTGA A01:02 ATGGCCGTCATGGCGCCCCGAACCCTCCTCCTGCTACTCTCGGGGGCCCTGGCCCTzGACCCAGACCTGGGCGGzGTGAGTGCGGGGTCGGGAGGGAAACCGCCTCTGCGGGGAGAAGCAAGGGGCCCTCCTGGCGGGGGCGCAGGACCGGGGGAGCCGCGCCGGGAGGAGGGTCGGTCAGGTCTCAGCCACTGCTCGCCCCCAGGCTCCCzACTCCATGAGGTATTTCTCCACATCCGTGTCCCGGCCCGGCAGTGGAGAzGCCzCCGCTTCATCGCAGTGGGCzTACGTGGACGzACACGzCAGTTCGTGCGGTTCGACAGCGACGCCGCGAGCCAGAAGATGGAGCCGzCGGGCGCCGTGGATAGAGCAGGAGGGGCCGGAGTATTGGGACCAGGzAGACACGGAzATATGAAGGCCCACTCACAGACTGACCGAGCGAACCTGGGGACCCTGCGCGGCTACTACAACCAGAGCGAGGACGGTGAGTGACCCCGGCCCGGGGzCGCAGGTCACGACCzCCTCATCCCCCzACGGACGGGCCAGGTCGCCCACAGTCTCCGGGTCCGAGATCCACCCCGAAGCCGCGGGACTCCGAGACCCTTGTCCCGGGAGAGGCCCAGGCGCCTTTACzCCGGTTTCATTTTCAGTTTAGGCCAAAAAzTCCCCCCzGGGTTGGTCGGGGCGGGGCGGGGCzTCGGGGGACzTGGGCTGACCGCGGGGTCGGGGCCAGGTTCTCACACCzATCCAGATAATGTATGGCTGCGACGTGGGGCCGGzACGGGCGCTTCCTCCGCGGGTACCGGCAzGGACGCCTACGACGGCAAGGATTAzCATCGCCCTGAzACzGAGGACCTGCGCTCTTGGACCGCGzGCGGACATGGCAGzCTCAGATCACCAAGCGCzAAGTzGGGAGzGCGGTCCAzTGCGGCzGGAGCAGCGGAGAGTCTACCTGGAGGGCCGGzTGCGTGzGACGGGCTCCGCzAGATAzCCTGGAGAACGGGAAGGAGACGCTGCAGCzGCACGGGTACCAGGGGCCACGGGGCGzCCTCCCTGATCGCCTzATzAGATCTCCCGGGCTGGCCTCzCCACAAGGAGGGGAGACAATTGGGACCAACACTAGAATATCACCCTCCCTCTzGGTCCTGAGGGAGAGGAATCCTCCTGGGTTTCCAGATCCTGTACCAGAGAGTGACTCTGAGGTTCCGCCCTGCTCTCTGACACAATTAAGGGATAAAAzTCTCTGAAGGAGTGACGGGAAGACGATCCCTCGAzATACTGATGAGTGGTTCCCTTTGACACzCGGCAGCAGCCTTGGGCCCGTGACTTTTCCTCTCAGGCCTTGTTCTCTGCTTCACACTCAATGTGTGTGzGGGGzTCTGAGTCCAGCACTTCTGAGTCTCTCAGCCTCCACTCAGGTCAGGACCAGAAGTCGCTGTTCCCTTCTCzAGGGAzATAGAAGATTATCCCAGGTGCCTGTGTCCAGGCTGGTGTCTGGGTTCTGTGCTCTCTTCCCCATCCCGGGTGTCCTGTCCATTCTCAAGATGGCCACAzTGCGTGCTGGTGGAGTGTCCCATGACAGATGCAAAATGCCTGAATTTTzCTGACTCTTCCCGTCAGACCCCCCCzAAGACACATATGACCCACCACCCCATCTCTGACCATGAGGCCACCCTGAGGTGCTGGGCCCTGGGCTTCTACCCTGCGGAGATCACACTGACCTGGCAGCGGGATGGGGAGGACzCAGACCCAGGACACGGAGCTCGTGGAGACCAGGCCTGCzAGGGGATGGAACCTTCCAGAAGTGGGCGGCTGTGGTGGTGCCTTCTGGAGAGGAGCAGAGATACACCTGCCATGTGCAGCATGAGGGTCTGCCCAAGCCCCTCACCCTGAGATGGGGTAAGGAGGGAGATGGGGGTGTCATGTCTCTTAGGGAAAGCzAGGAGCCTCTCTGGAGACCTTTAGCAGGGTCAGGGCCzCCTCACCTTCCCCTCTTTTCCCAGAGCTGTCTTCCCAGCCCACCATCCCCATCGTGGGCATCATTGCTGGCCTGGTTCTCCTTGGAGCTGTGATCACTGGAGCTGTGGTCGCTGCCGTGATGTGGAGGAGGAAGAGCTCAGGTGGAGzAAGGGGTGAAGGGTGGGGTCTGAGATTTCTTGTCTCACTGAGGGTTCCAAGCCCCAGCTAGAAATGTGCCCTGTCTCATTACTGGGAAGCACCTTCCACAATCATGGGCCGACCCAGCCTGGGCCCTGTGTGCCAGCACTTACTCTTTTGTAAAGCACCTGTTAAAATGAAGGACAGATTTATCACCTTGATTACGGCGGTGATGGGACCTGATCCCAGCAGTCACAAGTCACAGGGGAAGGTCCCTGAGGACAGACCTCAGGAGGGCTATTGGTCCAGGACCCACACCTGCTTTCTTCATGTTTCCTGATCCCGCCCTGGGTCTGCAGTCACACATTTCTGGAAACTTCTCTGGGGTCCAAGACTAGGAGGTTCCTCTAGGACCTTAAGGCCCTGGCTCCTTTCTGGTATCTCACAGGACATTTTCTTCCCACAGATAGAAAAGGAGGGAGTTACACTCAGGCTGCAAGTAAGTATGAAGGAGGCTGATGCCTGAGGTCCTTGGGATATTGTGTTTGGGzAGCCCATGGGGGAGCTCACCCACCCCACAATTCCTCCTCTAGCCACATCTTCTGTGGGATCTGACCAGGTTCTGTTTTTGTTCTACCCCAGGCAGTGACAGTGCCCAGGGCTCTGATGTGTCTCTCACAGCTTGTAAAGGTGAGAGCTTGGAGGGCCTGATGTGTGTTGGGTGTTGGGTGGAACAGTGGACACAGCTGTGCTATGGGGTTTCTTTGCGTTGGATGTATTGAGCATGCGATGGGCTGTTTAAGGTGTGAzCCCCTCACTGTGATGGATATGAATTTGTTCATGAATATTTTTTTCTATAGTGTGA A01:03 ATGGCCGTCATGGCGCCCCGAACCCTCCTCCTGCTACTCTCGGGGGCCCTGGCCCTzGACCCAGACCTGGGCGGzGTGAGTGCGGGGTCGGGAGGGAAACCGCCTCTGCGGGGAGAAGCAAGGGGCCCTCCTGGCGGGGGCGCAGGACCGGGGGAGCCGCGCCGGGAGGAGGGTCGGGCAGGTCTCAGCCACTGCTCGCCCCCAGGCTCCCzACTCCATGAGGTATTTCTTCACATCCGTGTCCCGGCCCGGCCGCGGGGAzGCCzCCGCTTCATCGCCGTGGGCzTACGTGGACGzACACGzCAGTTCGTGCGGTTCGACAGCGACGCCGCGAGCCAGAAGATGGAGCCGzCGGGCGCCGTGGATAGAGCAGGAGGGGCCGGAGTATTGGGACCAGGzAGACACGGAzATATGAAGGCCCACTCACAGACTGACCGAGCGAACCTGGGGACCCTGCGCGGCTACTACAACCAGAGCGAGGACGGTGAGTGACCCCGGCCCGGGGzCGCAGGTCACGACCzCCTCATCCCCCzACGGACGGGCCAGGTCGCCCACAGTCTCCGGGTCCGAGATCCACCCCGAAGCCGCGGGACTCCGAGACCCTTGTCCCGGGAGAGGCCCAGGCGCCTTTACzCCGGTTTCATTTTCAGTTTAGGCCAAAAAzTCCCCCCzGGGTTGGTCGGGGCGGGGCGGGGCzTCGGGGGACzTGGGCTGACCGCGGGGTCGGGGCCAGGTTCTCACACCzATCCAGATGATGTATGGCTGCGACGTGGGGCCGGzACGGGCGCTTCCTCCGCGGGTACCGGCAzGGACGCCTACGACGGCAAGGATTAzCATCGCCCTGAzACzGAGGACCTGCGCTCTTGGACCGCGzGCGGACATGGCAGzCTCAGATCACCAAGCGCzAAGTzGGGAGzGCGGTCCAzTGCGGCzGGAGCAGCGGAGAGTCTACCTGGAGGGCCGGzTGCGTGzGACGGGCTCCGCzAGATAzCCTGGAGAACGGGAAGGAGACGCTGCAGCzGCACGGGTACCAGGGGCCACGGGGCGzCCTCCCTGATCGCCTzATzAGATCTCCCGGGCTGGCCTCzCCACAAGGAGGGGAGACAATTGGGACCAACACTAGAATATCACCCTCCCTCTzGGTCCTGAGGGAGAGGAATCCTCCTGGGTTTCCAGATCCTGTACCAGAGAGTGACTCTGAGGTTCCGCCCTGCTCTCTGACACAATTAAGGGATAAAAzTCTCTGAAGGAGTGACGGGAAGACGATCCCTCGAzATACTGATGAGTGGTTCCCTTTGACACzCGGCAGCAGCCTTGGGCCCGTGACTTTTCCTCTCAGGCCTTGTTCTCTGCTTCACACTCAATGTGTGTGzGGGGzTCTGAGTCCAGCACTTCTGAGTCTCTCAGCCTCCACTCAGGTCAGGACCAGAAGTCGCTGTTCCCTTCTCzAGGGAzATAGAAGATTATCCCAGGTGCCTGTGTCCAGGCTGGTGTCTGGGTTCTGTGCTCTCTTCCCCATCCCGGGTGTCCTGTCCATTCTCAAGATGGCCACAzTGCGTGCTGGTGGAGTGTCCCATGACAGATGCAAAATGCCTGAATTTTzCTGACTCTTCCCGTCAGACCCCCCCzAAGACACATATGACCCACCACCCCATCTCTGACCATGAGGCCACCCTGAGGTGCTGGGCCCTGGGCTTCTACCCTGCGGAGATCACACTGACCTGGCAGCGGGATGGGGAGGACzCAGACCCAGGACACGGAGCTCGTGGAGACCAGGCCTGCzAGGGGATGGAACCTTCCAGAAGTGGGCGGCTGTGGTGGTGCCTTCTGGAGAGGAGCAGAGATACACCTGCCATGTGCAGCATGAGGGTCTGCCCAAGCCCCTCACCCTGAGATGGGGTAAGGAGGGAGATGGGGGTGTCATGTCTCTTAGGGAAAGCzAGGAGCCTCTCTGGAGACCTTTAGCAGGGTCAGGGCCzCCTCACCTTCCCCTCTTTTCCCAGAGCTGTCTTCCCAGCCCACCATCCCCATCGTGGGCATCATTGCTGGCCTGGTTCTCCTTGGAGCTGTGATCACTGGAGCTGTGGTCGCTGCTGTGATGTGGAGGAGGAAGAGCTCAGGTGGAGzAAGGGGTGAAGGGTGGGGTCTGAGATTTCTTGTCTCACTGAGGGTTCCAAGCCCCAGCTAGAAATGTGCCCTGTCTCATTACTGGGAAGCACCTTCCACAATCATGGGCCGACCCAGCCTGGGCCCTGTGTGCCAGCACTTACTCTTTTGTAAAGCACCTGTTAAAATGAAGGACAGATTTATCACCTTGATTACGGCGGTGATGGGACCTGATCCCAGCAGTCACAAGTCACAGGGGAAGGTCCCTGAGGACAGACCTCAGGAGGGCTATTGGTCCAGGACCCACACCTGCTTTCTTCATGTTTCCTGATCCCGCCCTGGGTCTGCAGTCACACATTTCTGGAAACTTCTCTGGGGTCCAAGACTAGGAGGTTCCTCTAGGACCTTAAGGCCCTGGCTCCTTTCTGGTATCTCACAGGACATTTTCTTCCCACAGATAGAAAAGGAGGGAGTTACACTCAGGCTGCAAGTAAGTATGAAGGAGGCTGATGCCTGAGGTCCTTGGGATATTGTGTTTGGGzAGCCCATGGGGGAGCTCACCCACCCCACAATTCCTCCTCTAGCCACATCTTCTGTGGGATCTGACCAGGTTCTGTTTTTGTTCTACCCCAGGCAGTGACAGTGCCCAGGGCTCTGATGTGTCTCTCACAGCTTGTAAAGGTGAGAGCTTGGAGGGCCTGATGTGTGTTGGGTGTTGGGTGGAACAGTGGACACAGCTGTGCTATGGGGTTTCTTTGCGTTGGATGTATTGAGCATGCGATGGGCTGTTTAAGGTGTGAzCCCCTCACTGTGATGGATATGAATTTGTTCATGAATATTTTTTTCTATAGTGTGA A01:04 ATGGCCGTCATGGCGCCCCGAACCCTCCTCCTGCTACTCTCGGGGGCCCTGGCCCTzGACCCAGACCTGGGCGGzGTGAGTGCGGGGTCGGGAGGGAAACCGCCTCTGCGGGGAGAAGCAAGGGGCCCTCCTGGCGGGGGCGCAGGACCGGGGGAGCCGCGCCGGGAGGAGGGTCGGGCAGGTCTCAGCCACTGCTCGCCCCCAGGCTCCCzACTCCATGAGGTATTTCTTCACATCCGTGTCCCGGCCCGGCCGCGGGGAzGCCzCCGCTTCATCGCCGTGGGCzTACGTGGACGzACACGzCAGTTCGTGCGGTTCGACAGCGACGCCGCGAGCCAGAAGATGGAGCCGzCGGGCGCCGTGGATAGAGCAGGAGGGGCCGGAGTATTGGGACCAGGzAGACACGGAzATATGAAGGCCCACTCACAGACTGACCGAGCGAACCTGGGGACCCTGCGCGGCTACTACAACCAGAGCGAGGACGGTGAGTGACCCCGGCCCGGGGzCGCAGGTCACGACCzCCTCATCCCCCzACGGACGGGCCAGGTCGCCCACAGTCTCCGGGTCCGAGATCCACCCCGAAGCCGCGGGACTCCGAGACCCTTGTCCCGGGAGAGGCCCAGGCGCCTTTACzCCGGTTTCATTTTCAGTTTAGGCCAAAAAzTCCCCCCzGGGTTGGTCGGGGCGGGGCGGGGCzTCGGGGGACzTGGGCTGACCGCGGGGTCGGGGCCAGGTTCTCACACCzATCCAGATAATGTATGGCTGCGACGTGGGGCCGGzACGGGCGCTTCCTCCGCGGGTACCGGCAzGGACGCCTACGACGGCAAGGATTAzCATCGCCCTGAzACzGAGGACCTGCGCTCTTGGACCGCGzGCGGACATGGCAGzCTCAGATCACCAAGCGCzAAGTzGGGAGzGCGGTCCAzTGCGGCzGGAGCAGCGGAGAGTCTACCTGGAGGGCCGGzTGCGTGzGACGGGCTCCGCzAGATAzCCTGGAGAACGGGAAGGAGACGCTGCAGCzGCACGGGTACCAGGGGCCACGGGGCGzCCTCCCTGATCGCCTzATzAGATCTCCCGGGCTGGCCTCzCCACAAGGAGGGGAGACAATTGGGACCAACACTAGAATATCACCCTCCCTCTzGGTCCTGAGGGAGAGGAATCCTCCTGGGTTTCCAGATCCTGTACCAGAGAGTGACTCTGAGGTTCCGCCCTGCTCTCTGACACAATTAAGGGATAAAAzTCTCTGAAGGAGTGACGGGAAGACGATCCCTCGAzATACTGATGAGTGGTTCCCTTTGACACzCGGCAGCAGCCTTGGGCCCGTGACTTTTCCTCTCAGGCCTTGTTCTCTGCTTCACACTCAATGTGTGTGzGGGGzTCTGAGTCCAGCACTTCTGAGTCTCTCAGCCTCCACTCAGGTCAGGACCAGAAGTCGCTGTTCCCTTCTCzAGGGAzATAGAAGATTATCCCAGGTGCCTGTGTCCAGGCTGGTGTCTGGGTTCTGTGCTCTCTTCCCCATCCCGGGTGTCCTGTCCATTCTCAAGATGGCCACAzTGCGTGCTGGTGGAGTGTCCCATGACAGATGCAAAATGCCTGAATTTTzCTGACTCTTCCCGTCAGACCCCCCCZAAGACACATATGACCCACCACCCCATCTCTGACCATGAGGCCACCCTGAGGTGCTGGGCCCTGGGCTTCTACCCTGCGGAGATCACACTGACCTGGCAGCGGGATGGGGAGGACzCAGACCCAGGACACGGAGCTCGTGGAGACCAGGCCTGCzAGGGGATGGAACCTTCCAGAAGTGGGCGGCTGTGGTGGTGCCTTCTGGAGAGGAGCAGAGATACACCTGCCATGTGCAGCATGAGGGTCTGCCCAAGCCCCTCACCCTGAGATGGGGTAAGGAGGGAGATGGGGGTGTCATGTCTCTTAGGGAAAGCzAGGAGCCTCTCTGGAGACCTTTAGCAGGGTCAGGGCCzCCTCACCTTCCCCTCTTTTCCCAGAGCTGTCTTCCCAGCCCACCATCCCCATCGTGGGCATCATTGCTGGCCTGGTTCTCCTTGGAGCTGTGATCACTGGAGCTGTGGTCGCTGCCGTGATGTGGAGGAGGAAGAGCTCAGGTGGAGzAAGGGGTGAAGGGTGGGGTCTGAGATTTCTTGTCTCACTGAGGGTTCCAAGCCCCAGCTAGAAATGTGCCCTGTCTCATTACTGGGAAGCACCTTCCACAATCATGGGCCGACCCAGCCTGGGCCCTGTGTGCCAGCACTTACTCTTTTGTAAAGCACCTGTTAAAATGAAGGACAGATTTATCACCTTGATTACGGCGGTGATGGGACCTGATCCCAGCAGTCACAAGTCACAGGGGAAGGTCCCTGAGGACAGACCTCAGGAGGGCTATTGGTCCAGGACCCACACCTGCTTTCTTCATGTTTCCTGATCCCGCCCTGGGTCTGCAGTCACACATTTCTGGAAACTTCTCTGGGGTCCAAGACTAGGAGGTTCCTCTAGGACCTTAAGGCCCTGGCTCCTTTCTGGTATCTCACAGGACATTTTCTTCCCACAGATAGAAAAGGAGGGAGTTACACTCAGGCTGCAAGTAAGTATGAAGGAGGCTGATGCCTGAGGTCCTTGGGATATTGTGTTTGGGzAGCCCATGGGGGAGCTCACCCACCCCACAATTCCTCCTCTAGCCACATCTTCTGTGGGATCTGACCAGGTTCTGTTTTTGTTCTACCCCAGGCAGTGACAGTGCCCAGGGCTCTGATGTGTCTCTCACAGCTTGTAAAGGTGAGAGCTTGGAGGGCCTGATGTGTGTTGGGTGTTGGGTGGAACAGTGGACACAGCTGTGCTATGGGGTTTCTTTGCGTTGGATGTATTGAGCATGCGATGGGCTGTTTAAGGTGTGAzCCCCTCACTGTGATGGATATGAATTTGTTCATGAATATTTTTTTCTATAGTGTGA A01:06 ATGGCCGTCATGGCGCCCCGAACCCTCCTCCTGCTACTCTCGGGGGCCCTGGCCCTzGACCCAGACCTGGGCGGzGTGAGTGCGGGGTCGGGAGGGAAACCGCCTCTGCGGGGAGAAGCAAGGGGCCCTCCTGGCGGGGGCGCAGGACCGGGGGAGCCGCGCCGGGAGGAGGGTCGGGCAGGTCTCAGCCACTGCTCGCCCCCAGGCTCCCzACTCCATGAGGTATTTCTTCACATCCGTGTCCCGGCCCGGCCGCGGGGAzGCCzCCGCTTCATCGCCGTGGGCzTACGTGGACGzACACGzCAGTTCGTGCGGTTCGACAGCGACGCCGCGAGCCAGAAGATGGAGCCGzCGGGCGCCGTGGATAGAGCAGGAGGGGCCGGAGTATTGGGACCAGGzAGACACGGAzATATGAAGGCCCACTCACAGACTGACCGAGCGAACCTGGGGACCCTGCGCGGCTACTACAACCAGAGCGAGGACGGTGAGTGACCCCGGCCCGGGGzCGCAGGTCACGACCzCCTCATCCCCCzACGGACGGGCCAGGTCGCCCACAGTCTCCGGGTCCGAGATCCACCCCGAAGCCGCGGGACTCCGAGACCCTTGTCCCGGGAGAGGCCCAGGCGCCTTTACzCCGGTTTCATTTTCAGTTTAGGCCAAAAAzTCCCCCCzGGGTTGGTCGGGGCGGGGCGGGGCzTCGGGGGACzTGGGCTGACCGCGGGGTCGGGGCCAGGTTCTCACACCzATCCAGATAATGTATGGCTGCGACGTGGGGCCGGzACGGGCGCTTCCTCCGCGGGTACCGGCAzGGACGCCTACGACGGCAAGGATTAzCATCGCCCTGAzACzGAGGACCTGCGCTCTTGGACCGCGzGCGGACATGGCAGzCTCAGATCACCAAGCGCzAAGTzGGGAGzGCGGTCCAzTGCGGCzGGAGCAGTTGAGAGCCTACCTGGAGGGCCGGzTGCGTGzGACGGGCTCCGCzAGATAzCCTGGAGAACGGGAAGGAGACGCTGCAGCzGCACGGGTACCAGGGGCCACGGGGCGzCCTCCCTGATCGCCTzATzAGATCTCCCGGGCTGGCCTCzCCACAAGGAGGGGAGACAATTGGGACCAACACTAGAATATCACCCTCCCTCTzGGTCCTGAGGGAGAGGAATCCTCCTGGGTTTCCAGATCCTGTACCAGAGAGTGACTCTGAGGTTCCGCCCTGCTCTCTGACACAATTAAGGGATAAAAzTCTCTGAAGGAGTGACGGGAAGACGATCCCTCGAzATACTGATGAGTGGTTCCCTTTGACACzCGGCAGCAGCCTTGGGCCCGTGACTTTTCCTCTCAGGCCTTGTTCTCTGCTTCACACTCAATGTGTGTGzGGGGzTCTGAGTCCAGCACTTCTGAGTCTCTCAGCCTCCACTCAGGTCAGGACCAGAAGTCGCTGTTCCCTTCTCzAGGGAzATAGAAGATTATCCCAGGTGCCTGTGTCCAGGCTGGTGTCTGGGTTCTGTGCTCTCTTCCCCATCCCGGGTGTCCTGTCCATTCTCAAGATGGCCACAzTGCGTGCTGGTGGAGTGTCCCATGACAGATGCAAAATGCCTGAATTTTzCTGACTCTTCCCGTCAGACCCCCCCzAAGACACATATGACCCACCACCCCATCTCTGACCATGAGGCCACCCTGAGGTGCTGGGCCCTGGGCTTCTACCCTGCGGAGATCACACTGACCTGGCAGCGGGATGGGGAGGACzCAGACCCAGGACACGGAGCTCGTGGAGACCAGGCCTGCzAGGGGATGGAACCTTCCAGAAGTGGGCGGCTGTGGTGGTGCCTTCTGGAGAGGAGCAGAGATACACCTGCCATGTGCAGCATGAGGGTCTGCCCAAGCCCCTCACCCTGAGATGGGGTAAGGAGGGAGATGGGGGTGTCATGTCTCTTAGGGAAAGCzAGGAGCCTCTCTGGAGACCTTTAGCAGGGTCAGGGCCzCCTCACCTTCCCCTCTTTTCCCAGAGCTGTCTTCCCAGCCCACCATCCCCATCGTGGGCATCATTGCTGGCCTGGTTCTCCTTGGAGCTGTGATCACTGGAGCTGTGGTCGCTGCCGTGATGTGGAGGAGGAAGAGCTCAGGTGGAGzAAGGGGTGAAGGGTGGGGTCTGAGATTTCTTGTCTCACTGAGGGTTCCAAGCCCCAGCTAGAAATGTGCCCTGTCTCATTACTGGGAAGCACCTTCCACAATCATGGGCCGACCCAGCCTGGGCCCTGTGTGCCAGCACTTACTCTTTTGTAAAGCACCTGTTAAAATGAAGGACAGATTTATCACCTTGATTACGGCGGTGATGGGACCTGATCCCAGCAGTCACAAGTCACAGGGGAAGGTCCCTGAGGACAGACCTCAGGAGGGCTATTGGTCCAGGACCCACACCTGCTTTCTTCATGTTTCCTGATCCCGCCCTGGGTCTGCAGTCACACATTTCTGGAAACTTCTCTGGGGTCCAAGACTAGGAGGTTCCTCTAGGACCTTAAGGCCCTGGCTCCTTTCTGGTATCTCACAGGACATTTTCTTCCCACAGATAGAAAAGGAGGGAGTTACACTCAGGCTGCAAGTAAGTATGAAGGAGGCTGATGCCTGAGGTCCTTGGGATATTGTGTTTGGGzAGCCCATGGGGGAGCTCACCCACCCCACAATTCCTCCTCTAGCCACATCTTCTGTGGGATCTGACCAGGTTCTGTTTTTGTTCTACCCCAGGCAGTGACAGTGCCCAGGGCTCTGATGTGTCTCTCACAGCTTGTAAAGGTGAGAGCTTGGAGGGCCTGATGTGTGTTGGGTGTTGGGTGGAACAGTGGACACAGCTGTGCTATGGGGTTTCTTTGCGTTGGATGTATTGAGCATGCGATGGGCTGTTTAAGGTGTGAzCCCCTCACTGTGATGGATATGAATTTGTTCATGAATATTTTTTTCTATAGTGTGA A01:09 ATGGCCGTCATGGCGCCCCGAACCCTCCTCCTGCTACTCTCGGGGGCCCTGGCCCTzGACCCAGACCTGGGCGGzGTGAGTGCGGGGTCGGGAGGGAAACCGCCTCTGCGGGGAGAAGCAAGGGGCCCTCCTGGCGGGGGCGCAGGACCGGGGGAGCCGCGCCGGGAGGAGGGTCGGGCAGGTCTCAGCCACTGCTCGCCCCCAGGCTCCCzACTCCATGAGGTATTTCTTCACATCCGTGTCCCGGCCCGGCCGCGGGGAzGCCzCCGCTTCATCGCCGTGGGCzTACGTGGACGzACACGzCAGTTAGTGCGGTTCGACAGCGACGCCGCGAGCCAGAAGATGGAGCCGzCGGGCGCCGTGGATAGAGCAGGAGGGGCCGGAGTATTGGGACCAGGzAGACACGGAzATATGAAGGCCCACTCACAGACTGACCGAGCGAACCTGGGGACCCTGCGCGGCTACTACAACCAGAGCGAGGACGGTGAGTGACCCCGGCCCGGGGzCGCAGGTCACGACCzCCTCATCCCCCzACGGACGGGCCAGGTCGCCCACAGTCTCCGGGTCCGAGATCCACCCCGAAGCCGCGGGGCTCCGAGACCCTTGTCCCGGGAGAGGCCCAGGCGCCTTTACzCCGGTTTCATTTTCAGTTTAGGCCAAAAAzTCCCCCCzGGGTTGGTCGGGGCGGGGCGGGGCzTCGGGGGACzTGGGCTGACCGCGGGGTCGGGGCCAGGTTCTCACACCzATCCAGATAATGTATGGCTGCGACGTGGGGCCGGzACGGGCGCTTCCTCCGCGGGTACCGGCAzGGACGCCTACGACGGCAAGGATTAzCATCGCCCTGAzACzGAGGACCTGCGCTCTTGGACCGCGzGCGGACATGGCAGzCTCAGATCACCAAGCGCzAAGTzGGGAGzGCGGTCCAzTGCGGCzGGAGCAGCGGAGAGTCTACCTGGAGGGCCGGzTGCGTGzGACGGGCTCCGCzAGATAzCCTGGAGAACGGGAAGGAGACGCTGCAGCzGCACGGGTACCAGGGGCCACGGGGCGzCCTCCCTGATCGCCTzATzAGATCTCCCGGGCTGGCCTCzCCACAAGGAGGGGAGACAATTGGGACCAACACTAGAATATCACCCTCCCTCTzGGTCCTGAGGGAGAGGAATCCTCCTGGGTTTCCAGATCCTGTACCAGAGAGTGACTCTGAGGTTCCGCCCTGCTCTCTGACACAATTAAGGGATAAAAzTCTCTGAAGGAGTGACGGGAAGACGATCCCTCGAzATACTGATGAGTGGTTCCCTTTGACACzCGGCAGCAGCCTTGGGCCCGTGACTTTTCCTCTCAGGCCTTGTTCTCTGCTTCACACTCAATGTGTGTGzGGGGzTCTGAGTCCAGCACTTCTGAGTCTCTCAGCCTCCACTCAGGTCAGGACCAGAAGTCGCTGTTCCCTTCTCzAGGGAzATAGAAGATTATCCCAGGTGCCTGTGTCCAGGCTGGTGTCTGGGTTCTGTGCTCTCTTCCCCATCCCGGGTGTCCTGTCCATTCTCAAGATGGCCACAzTGCGTGCTGGTGGAGTGTCCCATGACAGATGCAAAATGCCTGAATTTTzCTGACTCTTCCCGTCAGACCCCCCCzAAGACACATATGACCCACCACCCCATCTCTGACCATGAGGCCACCCTGAGGTGCTGGGCCCTGGGCTTCTACCCTGCGGAGATCACACTGACCTGGCAGCGGGATGGGGAGGACzCAGACCCAGGACACGGAGCTCGTGGAGACCAGGCCTGCzAGGGGATGGAACCTTCCAGAAGTGGGCGGCTGTGGTGGTGCCTTCTGGAGAGGAGCAGAGATACACCTGCCATGTGCAGCATGAGGGTCTGCCCAAGCCCCTCACCCTGAGATGGGGTAAGGAGGGAGATGGGGGTGTCATGTCTCTTAGGGAAAGCzAGGAGCCTCTCTGGAGACCTTTAGCAGGGTCAGGGCCzCCTCACCTTCCCCTCTTTTCCCAGAGCTGTCTTCCCAGCCCACCATCCCCATCGTGGGCATCATTGCTGGCCTGGTTCTCCTTGGAGCTGTGATCACTGGAGCTGTGGTCGCTGCCGTGATGTGGAGGAGGAAGAGCTCAGGTGGAGzAAGGGGTGAAGGGTGGGGTCTGAGATTTCTTGTCTCACTGAGGGTTCCAAGCCCCAGCTAGAAATGTGCCCTGTCTCATTACTGGGAAGCACCTTCCACAATCATGGGCCGACCCAGCCTGGGCCCTGTGTGCCAGCACTTACTCTTTTGTAAAGCACCTGTTAAAATGAAGGACAGATTTATCACCTTGATTACGGCGGTGATGGGACCTGATCCCAGCAGTCACAAGTCACAGGGGAAGGTCCCTGAGGACAGACCTCAGGAGGGCTATTGGTCCAGGACCCACACCTGCTTTCTTCATGTTTCCTGATCCCGCCCTGGGTCTGCAGTCACACATTTCTGGAAACTTCTCTGGGGTCCAAGACTAGGAGGTTCCTCTAGGACCTTAAGGCCCTGGCTCCTTTCTGGTATCTCACAGGACATTTTCTTCCCACAGATAGAAAAGGAGGGAGTTACACTCAGGCTGCAAGTAAGTATGAAGGAGGCTGATGCCTGAGGTCCTTGGGATATTGTGTTTGGGzAGCCCATGGGGGAGCTCACCCACCCCACAATTCCTCCTCTAGCCACATCTTCTGTGGGATCTGACCAGGTTCTGTTTTTGTTCTACCCCAGGCAGTGACAGTGCCCAGGGCTCTGATGTGTCTCTCACAGCTTGTAAAGGTGAGAGCTTGGAGGGCCTGATGTGTGTTGGGTGTTGGGTGGAACAGTGGACACAGCTGTGCTATGGGGTTTCTTTGCGTTGGATGTATTGAGCATGCGATGGGCTGTTTAAGGTGTGAzCCCCTCACTGTGATGGATATGAATTTGTTCATGAATATTTTTTTCTATAGTGTGA A01:11N ATGGCCGTCATGGCGCCCCGAACCCTCCTCCTGCTACTCTCGGGGGCCCTGGCCCTzGACCCAGACCTGGGCGGzGTGAGTGCGGGGTCGGGAGGGAAACCGCCTCTGCGGGGAGAAGCAAGGGGCCCTCCTGGCGGGGGCGCAGGACCGGGGGAGCCGCGCCGGGAGGAGGGTCGGGCAGGTCTCAGCCACTGCTCGCCCCCAGGCTCCCzACTCCATGAGGTATTTCTTCACATCCGTGTCCCGGCCCGGCCGCGGGGAzGCCzCCGCTTCATCGCCGTGGGCzTACGTGGACGzACACGzCAGTTCGTGCGGTTCGACAGCGACGCCGCGAGCCAGAAGATGGAGCCGzCGGGCGCCGTGGATAGAGCAGGAGGGGCCGGAGTATTGGGACCAGGzAGACACGGAzATATGAAGGCCCACTCACAGACTGACCGAGCGAACCTGGGGACCCTGCGCGGCTACTACAACCAGAGCGAGGACGGTGAGTGACCCCGGCCCGGGGzCGCAGGTCACGACCzCCTCATCCCCCzACGGACGGGCCAGGTCGCCCACAGTCTCCGGGTCCGAGATCCACCCCGAAGCCGCGGGACTCCGAGACCCTTGTCCCGGGAGAGGCCCAGGCGCCTTTACzCCGGTTTCATTTTCAGTTTAGGCCAAAAAzTCCCCCCzGGGTTGGTCGGGGCGGGGCGGGGCzTCGGGGGACzTGGGCTGACCGCGGGGTCGGGGCCAGGTTCTCACACCzATCCAGATAATGTATGGCTGCGACGTGGGGCCGGzACGGGCGCTTCCTCCGCGGGTACCGGCAzGGACGCCTACGACGGCAAGGATTAzCATCGCCCTGAzACzGAGGACCTGCGCTCTTGGACCGCGzGCGGACATGGCAGzCTCAGATCACCAAGCGCzAAGTzGGGAGzGCGGTCCAzTGCGGCzGGAGCAGCGGAGAGTCTACCTGGAGGGCCGGzTGCGTGzGACGGGCTCCGCzAGATAzCCTGGAGAACGGTAAGGAGACGCTGCAGCzGCACGGGTACCAGGGGCCACGGGGCGzCCTCCCTGATCGCCTzATzAGATCTCCCGGGCTGGCCTCzCCACAAGGAGGGGAGACAATTGGGACCAACACTAGAATATCACCCTCCCTCTzGGTCCTGAGGGAGAGGAATCCTCCTGGGTTTCCAGATCCTGTACCAGAGAGTGACTCTGAGGTTCCGCCCTGCTCTCTGACACAATTAAGGGATAAAAzTCTCTGAAGGAGTGACGGGAAGACGATCCCTCGAzATACTGATGAGTGGTTCCCTTTGACACzCGGCAGCAGCCTTGGGCCCGTGACTTTTCCTCTCAGGCCTTGTTCTCTGCTTCACACTCAATGTGTGTGzGGGGzTCTGAGTCCAGCACTTCTGAGTCTCTCAGCCTCCACTCAGGTCAGGACCAGAAGTCGCTGTTCCCTTCTCzAGGGAzATAGAAGATTATCCCAGGTGCCTGTGTCCAGGCTGGTGTCTGGGTTCTGTGCTCTCTTCCCCATCCCGGGTGTCCTGTCCATTCTCAAGATGGCCACAzTGCGTGCTGGTGGAGTGTCCCATGACAGATGCAAAATGCCTGAATTTTzCTGACTCTTCCCGTCAGACCCCCCCzAAGACACATATGACCCACCACCCCATCTCTGACCATGAGGCCACCCTGAGGTGCTGGGCCCTGGGCTTCTACCCTGCGGAGATCACACTGACCTGGCAGCGGGATGGGGAGGACzCAGACCCAGGACACGGAGCTCGTGGAGACCAGGCCTGCzAGGGGATGGAACCTTCCAGAAGTGGGCGGCTGTGGTGGTGCCTTCTGGAGAGGAGCAGAGATACACCTGCCATGTGCAGCATGAGGGTCTGCCCAAGCCCCTCACCCTGAGATGGGGTAAGGAGGGAGATGGGGGTGTCATGTCTCTTAGGGAAAGCzAGGAGCCTCTCTGGAGACCTTTAGCAGGGTCAGGGCCzCCTCACCTTCCCCTCTTTTCCCAGAGCTGTCTTCCCAGCCCACCATCCCCATCGTGGGCATCATTGCTGGCCTGGTTCTCCTTGGAGCTGTGATCACTGGAGCTGTGGTCGCTGCCGTGATGTGGAGGAGGAAGAGCTCAGGTGGAGzAAGGGGTGAAGGGTGGGGTCTGAGATTTCTTGTCTCACTGAGGGTTCCAAGCCCCAGCTAGAAATGTGCCCTGTCTCATTACTGGGAAGCACCTTCCACAATCATGGGCCGACCCAGCCTGGGCCCTGTGTGCCAGCACTTACTCTTTTGTAAAGCACCTGTTAAAATGAAGGACAGATTTATCACCTTGATTACGGCGGTGATGGGACCTGATCCCAGCAGTCACAAGTCACAGGGGAAGGTCCCTGAGGACAGACCTCAGGAGGGCTATTGGTCCAGGACCCACACCTGCTTTCTTCATGTTTCCTGATCCCGCCCTGGGTCTGCAGTCACACATTTCTGGAAACTTCTCTGGGGTCCAAGACTAGGAGGTTCCTCTAGGACCTTAAGGCCCTGGCTCCTTTCTGGTATCTCACAGGACATTTTCTTCCCACAGATAGAAAAGGAGGGAGTTACACTCAGGCTGCAAGTAAGTATGAAGGAGGCTGATGCCTGAGGTCCTTGGGATATTGTGTTTGGGzAGCCCATGGGGGAGCTCACCCACCCCACAATTCCTCCTCTAGCCACATCTTCTGTGGGATCTGACCAGGTTCTGTTTTTGTTCTACCCCAGGCAGTGACAGTGCCCAGGGCTCTGATGTGTCTCTCACAGCTTGTAAAGGTGAGAGCTTGGAGGGCCTGATGTGTGTTGGGTGTTGGGTGGAACAGTGGACACAGCTGTGCTATGGGGTTTCTTTGCGTTGGATGTATTGAGCATGCGATGGGCTGTTTAAGGTGTGAzCCCCTCACTGTGATGGATATGAATTTGTTCATGAATATTTTTTTCTATAGTGTGA A01:12 ATGGCCGTCATGGCGCCCCGAACCCTCCTCCTGCTACTCTCGGGGGCCCTGGCCCTzGACCCAGACCTGGGCGGzGTGAGTGCGGGGTCGGGAGGGAAACCGCCTCTGCGGGGAGAAGCAAGGGGCCCTCCTGGCGGGGGCGCAGGACCGGGGGAGCCGCGCCGGGAGGAGGGTCGGGCAGGTCTCAGCCACTGCTCGCCCCCAGGCTCCCzACTCCATGAGGTATTTCTTCACATCCGTGTCCCGGCCCGGCCGCGGGGAzGCCzCCGCTTCATCGCCGTGGGCzTACGTGGACGzACACGzCAGTTCGTGCGGTTCGACAGCGACGCCGCGAGCCAGAAGATGGAGCCGzCGGGCGCCGTGGATAGAGCAGGAGGGGCCGGAGTATTGGGACCAGGzAGACACGGAzATATGAAGGCCCACTCACAGACTGACCGAGCGAACCTGGGGACCCTGCGCGGCTACTACAACCAGAGCGAGGACGGTGAGTGACCCCGGCCCGGGGzCGCAGGTCACGACCzCCTCATCCCCCzACGGACGGGCCAGGTCGCCCACAGTCTCCGGGTCCGAGATCCACCCCGAAGCCGCGGGACTCCGAGACCCTTGTCCCGGGAGAGGCCCAGGCGCCTTTACzCCGGTTTCATTTTCAGTTTAGGCCAAAAAzTCCCCCCzGGGTTGGTCGGGGCGGGGCGGGGCzTCGGGGGACzTGGGCTGACCGCGGGGTCGGGGCCAGGTTCTCACACCzATCCAGATAATGTATGGCTGCGACGTGGGGCCGGzACGGGCGCTTCCTCCGCGGGTACCGGCAzGGACGCCTACGACGGCAAGGATTAzCATCGCCCTGAzACzGAGGACCTGCGCTCTTGGACCGCGzGCGGACATGGCAGzCTCAGATCACCAAGCGCzAAGTzGGGAGzGCGGCCCAzTGTGGCzGGAGCAGCAGAGAGCCTACCTGGAGGGCACGzTGCGTGzGACGGGCTCCGCzAGATAzCCTGGAGAACGGGAAGGAGACGCTGCAGCzGCACGGGTACCAGGGGCCACGGGGCGzCCTCCCTGATCGCCTzATzAGATCTCCCGGGCTGGCCTCzCCACAAGGAGGGGAGACAATTGGGACCAACACTAGAATATCACCCTCCCTCTzGGTCCTGAGGGAGAGGAATCCTCCTGGGTTTCCAGATCCTGTACCAGAGAGTGACTCTGAGGTTCCGCCCTGCTCTCTGACACAATTAAGGGATAAAAzTCTCTGAAGGAGTGACGGGAAGACGATCCCTCGAzATACTGATGAGTGGTTCCCTTTGACACzCGGCAGCAGCCTTGGGCCCGTGACTTTTCCTCTCAGGCCTTGTTCTCTGCTTCACACTCAATGTGTGTGzGGGGzTCTGAGTCCAGCACTTCTGAGTCTCTCAGCCTCCACTCAGGTCAGGACCAGAAGTCGCTGTTCCCTTCTCzAGGGAzATAGAAGATTATCCCAGGTGCCTGTGTCCAGGCTGGTGTCTGGGTTCTGTGCTCTCTTCCCCATCCCGGGTGTCCTGTCCATTCTCAAGATGGCCACAzTGCGTGCTGGTGGAGTGTCCCATGACAGATGCAAAATGCCTGAATTTTzCTGACTCTTCCCGTCAGACCCCCCCzAAGACACATATGACCCACCACCCCATCTCTGACCATGAGGCCACCCTGAGGTGCTGGGCCCTGGGCTTCTACCCTGCGGAGATCACACTGACCTGGCAGCGGGATGGGGAGGACzCAGACCCAGGACACGGAGCTCGTGGAGACCAGGCCTGCzAGGGGATGGAACCTTCCAGAAGTGGGCGGCTGTGGTGGTGCCTTCTGGAGAGGAGCAGAGATACACCTGCCATGTGCAGCATGAGGGTCTGCCCAAGCCCCTCACCCTGAGATGGGGTAAGGAGGGAGATGGGGGTGTCATGTCTCTTAGGGAAAGCzAGGAGCCTCTCTGGAGACCTTTAGCAGGGTCAGGGCCzCCTCACCTTCCCCTCTTTTCCCAGAGCTGTCTTCCCAGCCCACCATCCCCATCGTGGGCATCATTGCTGGCCTGGTTCTCCTTGGAGCTGTGATCACTGGAGCTGTGGTCGCTGCCGTGATGTGGAGGAGGAAGAGCTCAGGTGGAGzAAGGGGTGAAGGGTGGGGTCTGAGATTTCTTGTCTCACTGAGGGTTCCAAGCCCCAGCTAGAAATGTGCCCTGTCTCATTACTGGGAAGCACCTTCCACAATCATGGGCCGACCCAGCCTGGGCCCTGTGTGCCAGCACTTACTCTTTTGTAAAGCACCTGTTAAAATGAAGGACAGATTTATCACCTTGATTACGGCGGTGATGGGACCTGATCCCAGCAGTCACAAGTCACAGGGGAAGGTCCCTGAGGACAGACCTCAGGAGGGCTATTGGTCCAGGACCCACACCTGCTTTCTTCATGTTTCCTGATCCCGCCCTGGGTCTGCAGTCACACATTTCTGGAAACTTCTCTGGGGTCCAAGACTAGGAGGTTCCTCTAGGACCTTAAGGCCCTGGCTCCTTTCTGGTATCTCACAGGACATTTTCTTCCCACAGATAGAAAAGGAGGGAGTTACACTCAGGCTGCAAGTAAGTATGAAGGAGGCTGATGCCTGAGGTCCTTGGGATATTGTGTTTGGGzAGCCCATGGGGGAGCTCACCCACCCCACAATTCCTCCTCTAGCCACATCTTCTGTGGGATCTGACCAGGTTCTGTTTTTGTTCTACCCCAGGCAGTGACAGTGCCCAGGGCTCTGATGTGTCTCTCACAGCTTGTAAAGGTGAGAGCTTGGAGGGCCTGATGTGTGTTGGGTGTTGGGTGGAACAGTGGACACAGCTGTGCTATGGGGTTTCTTTGCGTTGGATGTATTGAGCATGCGATGGGCTGTTTAAGGTGTGAzCCCCTCACTGTGATGGATATGAATTTGTTCATGAATATTTTTTTCTATAGTGTGA A01:14 ATGGCCGTCATGGCGCCCCGAACCCTCCTCCTGCTACTCTCGGGGGCCCTGGCCCTzGACCCAGACCTGGGCGGzGTGAGTGCGGGGTCGGGAGGGAAACCGCCTCTGCGGGGAGAAGCAAGGGGCCCTCCTGGCGGGGGCGCAGGACCGGGGGAGCCGCGCCGGGAGGAGGGTCGGGCAGGTCTCAGCCACTGCTCGCCCCCAGGCTCCCzACTCCATGAGGTATTTCTTCACATCCGTGTCCCGGCCCGGCCGCGGGGAzGCCzCCGCTTCATCGCCGTGGGCzTACGTGGACGzACACGzCAGTTCGTGCGGTTCGACAGCGACGCCGCGAGCCAGAAGATGGAGCCGzCGGGCGCCGTGGATAGAGCAGGAGGGGCCGGAGTATTGGGACCAGGzAGACACGGAzATATGAAGGCCCACTCACAGACTGACCGAGCGAACCTGGGGACCCTGCGCGGCTACTACAACCAGAGCGAGGACGGTGAGTGACCCCGGCCCGGGGzCGCAGGTCACGACCzCCTCATCCCCCzACGGACGGGCCAGGTCGCCCACAGTCTCCGGGTCCGAGATCCACCCCGAAGCCGCGGGACTCCGAGACCCTTGTCCCGGGAGAGGCCCAGGCGCCTTTACzCCGGTTTCATTTTCAGTTTAGGCCAAAAAzTCCCCCCzGGGTTGGTCGGGGCGGGGCGGGGCzTCGGGGGACzTGGGCTGACCGCGGGGTCGGGGCCAGGTTCTCACACCzATCCAGATAATGTATGGCTGCGACGTGGGGCCGGzACGGGCGCTTCCTCCGCGGGTACCGGCAzGGACGCCTACGACGGCAAGGATTAzCATCGCCCTGAzACzGAGGACCTGCGCTCTTGGACCGCGzGCGGACATGGCAGzCTCAGATCACCAAGCGCzAAGTzGGGAGzGCGGTCCAzTGCGGCzGGAGCAGCGGAGAGTCTACCTGGAGGGCACGzTGCGTGzGACGGGCTCCGCzAGATAzCCTGGAGAACGGGAAGGAGACGCTGCAGCzGCACGGGTACCAGGGGCCACGGGGCGzCCTCCCTGATCGCCTzATzAGATCTCCCGGGCTGGCCTCzCCACAAGGAGGGGAGACAATTGGGACCAACACTAGAATATCACCCTCCCTCTzGGTCCTGAGGGAGAGGAATCCTCCTGGGTTTCCAGATCCTGTACCAGAGAGTGACTCTGAGGTTCCGCCCTGCTCTCTGACACAATTAAGGGATAAAAzTCTCTGAAGGAGTGACGGGAAGACGATCCCTCGAzATACTGATGAGTGGTTCCCTTTGACACzCGGCAGCAGCCTTGGGCCCGTGACTTTTCCTCTCAGGCCTTGTTCTCTGCTTCACACTCAATGTGTGTGzGGGGzTCTGAGTCCAGCACTTCTGAGTCTCTCAGCCTCCACTCAGGTCAGGACCAGAAGTCGCTGTTCCCTTCTCzAGGGAzATAGAAGATTATCCCAGGTGCCTGTGTCCAGGCTGGTGTCTGGGTTCTGTGCTCTCTTCCCCATCCCGGGTGTCCTGTCCATTCTCAAGATGGCCACAzTGCGTGCTGGTGGAGTGTCCCATGACAGATGCAAAATGCCTGAATTTTzCTGACTCTTCCCGTCAGACCCCCCCzAAGACACATATGACCCACCACCCCATCTCTGACCATGAGGCCACCCTGAGGTGCTGGGCCCTGGGCTTCTACCCTGCGGAGATCACACTGACCTGGCAGCGGGATGGGGAGGACzCAGACCCAGGACACGGAGCTCGTGGAGACCAGGCCTGCzAGGGGATGGAACCTTCCAGAAGTGGGCGGCTGTGGTGGTGCCTTCTGGAGAGGAGCAGAGATACACCTGCCATGTGCAGCATGAGGGTCTGCCCAAGCCCCTCACCCTGAGATGGGGTAAGGAGGGAGATGGGGGTGTCATGTCTCTTAGGGAAAGCzAGGAGCCTCTCTGGAGACCTTTAGCAGGGTCAGGGCCzCCTCACCTTCCCCTCTTTTCCCAGAGCTGTCTTCCCAGCCCACCATCCCCATCGTGGGCATCATTGCTGGCCTGGTTCTCCTTGGAGCTGTGATCACTGGAGCTGTGGTCGCTGCCGTGATGTGGAGGAGGAAGAGCTCAGGTGGAGzAAGGGGTGAAGGGTGGGGTCTGAGATTTCTTGTCTCACTGAGGGTTCCAAGCCCCAGCTAGAAATGTGCCCTGTCTCATTACTGGGAAGCACCTTCCACAATCATGGGCCGACCCAGCCTGGGCCCTGTGTGCCAGCACTTACTCTTTTGTAAAGCACCTGTTAAAATGAAGGACAGATTTATCACCTTGATTACGGCGGTGATGGGACCTGATCCCAGCAGTCACAAGTCACAGGGGAAGGTCCCTGAGGACAGACCTCAGGAGGGCTATTGGTCCAGGACCCACACCTGCTTTCTTCATGTTTCCTGATCCCGCCCTGGGTCTGCAGTCACACATTTCTGGAAACTTCTCTGGGGTCCAAGACTAGGAGGTTCCTCTAGGACCTTAAGGCCCTGGCTCCTTTCTGGTATCTCACAGGACATTTTCTTCCCACAGATAGAAAAGGAGGGAGTTACACTCAGGCTGCAAGTAAGTATGAAGGAGGCTGATGCCTGAGGTCCTTGGGATATTGTGTTTGGGzAGCCCATGGGGGAGCTCACCCACCCCACAATTCCTCCTCTAGCCACATCTTCTGTGGGATCTGACCAGGTTCTGTTTTTGTTCTACCCCAGGCAGTGACAGTGCCCAGGGCTCTGATGTGTCTCTCACAGCTTGTAAAGGTGAGAGCTTGGAGGGCCTGATGTGTGTTGGGTGTTGGGTGGAACAGTGGACACAGCTGTGCTATGGGGTTTCTTTGCGTTGGATGTATTGAGCATGCGATGGGCTGTTTAAGGTGTGAzCCCCTCACTGTGATGGATATGAATTTGTTCATGAATATTTTTTTCTATAGTGTGA A01:16N ATGGCCGTCATGGCGCCCCGAACCCTCCTCCTGCTACTCTCGGGGGCCCTGGCCCTzGACCCAGACCTGGGCGGzGTGAGTGCGGGGTCGGGAGGGAAACCGCCTCTGCGGGGAGAAGCAAGGGGCCCTCCTGGCGGGGGCGCAGGACCGGGGGAGCCGCGCCGGGAGGAGGGTCGGGCAGGTCTCAGCCACTGCTCGCCCCCAGGCTCCCzACTCCATGAGGTATTTCTTCACATCCGTGTCCCGGCCCGGCCGCGGGGAzGCCzCCGCTTCATCGCCGTGGGCzTACGTGGACGzACACGzCAGTTCGTGCGGTTCGACAGCGACGCCGCGAGCCAGAAGATGGAGCCGzCGGGCGCCGTGGATAGAGCAGGAGGGGCCGGAGTATTGGGACCAGGzAGACACGGAzATATGAAGGCCCACTCACAGACTGACCGAGCGAACCTGGGGACCCTGCGCGGCTACTACAACCAGAGCGAGGACGGTGAGTGACCCCGGCCCGGGGzCGCAGGTCACGACCzCCTCATCCCCCzACGGACGGGCCAGGTCGCCCACAGTCTCCGGGTCCGAGATCCACCCCGAAGCCGCGGGACTCCGAGACCCTTGTCCCGGGAGAGGCCCAGGCGCCTTTACzCCGGTTTCATTTTCAGTTTAGGCCAAAAAzTCCCCCCzGGGTTGGTCGGGGCGGGGCGGGGCzTCGGGGGACzTGGGCTGACCGCGGGGTCGGGGCCAGGTTCTCACACCzATCCAGATAATGTATGGCTGCGACGTGGGGCCGGzACGGGCGCTTCCTCCGCGGGTACCGGCAzGGACGCCTACGACGGCAAGGATTAzCATCGCCCTGAzACzGAGGACCTGCGCTCTTGGACCGCGzGCGGACATGGCAGzCTCAGATCACCAAGCGCzAAGTzGGGAGzGCGGTCCAzTGCGGCZGGAGCAGCGGAGAGTCTACCTGGAGGGCCGGzTGCGTGzGACGGGCTCCGCzAGATAzCCTGGAGAACGGGAAGGAGACGCTGCAGCzGCACGGGTACCAGGGGCCACGGGGCGzCCTCCCTGATCGCCTzATzAGATCTCCCGGGCTGGCCTCzCCACAAGGAGGGGAGACAATTGGGACCAACACTAGAATATCACCCTCCCTCTzGGTCCTGAGGGAGAGGAATCCTCCTGGGTTTCCAGATCCTGTACCAGAGAGTGACTCTGAGGTTCCGCCCTGCTCTCTGACACAATTAAGGGATAAAAzTCTCTGAAGGAGTGACGGGAAGACGATCCCTCGAzATACTGATGAGTGGTTCCCTTTGACACzCGGCAGCAGCCTTGGGCCCGTGACTTTTCCTCTCAGGCCTTGTTCTCTGCTTCACACTCAATGTGTGTGzGGGGzTCTGAGTCCAGCACTTCTGAGTCTCTCAGCCTCCACTCAGGTCAGGACCAGAAGTCGCTGTTCCCTTCTCzAGGGAzATAGAAGATTATCCCAGGTGCCTGTGTCCAGGCTGGTGTCTGGGTTCTGTGCTCTCTTCCCCATCCCGGGTGTCCTGTCCATTCTCAAGATGGCCACAzTGCGTGCTGGTGGAGTGTCCCATGACAGATGCAAAATGCCTGAATTTTzCTGACTCTTCCCGTCAGACCCCCCCzAAGACACATATGACCCACCACCCCATCTCTGACCATGAGGCCACCCTGAGGTGCTGGGCCCTGGGCTTCTACCCTGCGGAGATCACACTGACCTGGCAGCGGGATGGGGAGGACzCAGACCCAGGACACGGAGCTCGTGGAGACCAGGCCTGCzAGGGGATGGAACCTTCCAGAAGTGGGCGGCTGTGGTGGTGCCTTCTGGAGAGGAGCAGAGATACACCTGCCATGTGCAGCATGAGGGTCTGCCCAAGCCCCTCACCCTGAGATGGGGTAAGGAGGGAGATGGGGGTGTCATGTCTCTTAGGGAAAGCzAGGAGCCTCTCTGGAGACCTTTAGCAGGGTCAGGGCCzCCTCACCTTCCCCTCTTTTCCCAGAGCTGTCTTCCCAGCCCACCATCCCCATCGTGGGCATCATTGCTGGCCTGGTTCTCCTTGGAGCTGTGATCACTGGAGCTGTGGTCGCTGCCGTGATGTGGAGGAGGAAGAGCTCAGGTGGAGzAAGGGGTGAAGGGTGGGGTCTGAGATTTCTTGTCTCACTGAGGGTTCCAAGCCCCAGCTAGAAATGTGCCCTGTCTCATTACTGGGAAGCACCTTCCACAATCATGGGCCGACCCAGCCTGGGCCCTGTGTGCCAGCACTTACTCTTTTGTAAAGCACCTGTTAAAATGAAGGACAGATTTATCACCTTGATTACGGCGGTGATGGGACCTGATCCCAGCAGTCACAAGTCACAGGGGAAGGTCCCTGAGGACAGACCTCAGGAGGGCTATTGGTCCAGGACCCACACCTGCTTTCTTCATGTTTCCTGATCCCGCCCTGGGTCTGCAGTCACACATTTCTGGAAACTTCTCTGGGGTCCAAGACTAGGAGGTTCCTCTAGGACCTTAAGGCCCTGGCTCCTTTCTGGTATCTCACAGGACATTTTCTTCCCACAGATAGAAAAGGAGGGAGTTACACTCAGGCTGCAAGTAAGTATGAAGGAGGCTGATGCCTGAGGTCCTTGGGATATTGTGTTTGGGzAGCCCATGGGGGAGCTCACCCACCCCACAATTCCTCCTCTAGCCACATCTTCTGTGGGATCTGACCAGGTTCTGTTTTTGTTCTACCCCAGGCAGTGACAGTGCCCAGGGCTCTGATGTGTCTCTCACAGCTTGTAAAGGTGAGAGCTTGGAGGGCCTGATGTGTGTTGGGTGTTGGGTGGAACAGTGGACACAGCTGTGCTATGGGGTTTCTTTGCGTTGGATGTATTGAGCATGCGATGGGCTGTTTAAGGTGTGAzCCCCTCACTGTGATGGATATGAATTTGTTCATGAATATTTTTTTCTATAGTGTGA

3) *.chr6.hg18.chped -> this and the log file are the only chped I have

2016130104315 2016130104315 0 0 0 -9 A01:01 A02:01 B08:01 B27:05 C02:02 C07:01 0 0 0 0 0 0 DQB102:01 DQB106:02 DRB115:01 DRB103:01 2016130104316 2016130104316 0 0 0 -9 A02:05 A26:01 B55:01 B55:01 C01:02 C12:03 0 0 0 0 0 0 DQB102:01 DQB103:01 DRB103:01 DRB113:03 2016130104317 2016130104317 0 0 0 -9 A03:01 A03:01 B35:01 B27:05 C01:02 C04:01 0 0 0 0 0 0 DQB105:01 DQB105:01 DRB101:01 DRB101:01 2016130104324 2016130104324 0 0 0 -9 A02:01 A25:01 B18:01 B44:02 C07:04 C12:03 0 0 0 0 0 0 DQB106:02 DQB103:02 DRB111:01 DRB115:01 2016130104326 2016130104326 0 0 0 -9 A68:01 A02:01 B07:02 B27:05 C03:03 C07:02 0 0 0 0 0 0 DQB103:02 DQB106:03 DRB104:01 DRB115:01 2016130104327 2016130104327 0 0 0 -9 A01:01 A02:01 B08:01 B35:01 C04:01 C07:01 0 0 0 0 0 0 DQB102:01 DQB105:01 DRB101:01 DRB103:01 2016130104340 2016130104340 0 0 0 -9 A11:01 A30:01 B13:02 B51:01 C01:02 C06:02 0 0 0 0 0 0 DQB102:02 DQB105:03 DRB107:01 DRB107:01 2016130104355 2016130104355 0 0 0 -9 A02:01 A02:01 B15:01 B18:01 C03:03 C07:01 0 0 0 0 0 0 DQB106:03 DQB103:01 DRB112:01 DRB113:01 2016130104356 2016130104356 0 0 0 -9 A24:02 A24:02 B13:02 B44:05 C02:02 C06:02 0 0 0 0 0 0 DQB102:02 DQB106:02 DRB107:01 DRB115:01 2016130104364 2016130104364 0 0 0 -9 A03:01 A11:01 B07:02 B40:02 C02:02 C07:02 0 0 0 0 0 0 DQB106:03 DQB106:03 DRB113:01 DRB113:01

• That was my mistake, when opening the issues I anonymized the name of the directory and I made a mistake, I apologize!

[pcibin]

Hello!

I tried to have a look at it in the meanwhile, but I am not sure what I am doing wrong...

[WansonChoi]

@pcibin

Last week, I replicated the error in my system but haven't found the cause yet. I checked the error comes near this line.

https://github.com/WansonChoi/HATK/blob/84ec5a63104113ba0abf9bfc3867b6f3d7631193/bMarkerGenerator/src/HLAtoSequences.py#L197

It's really bizarre, because the hped file looks perfectly fine...

I have to take a look more, but this week of mine is too heavily occupied with other things to do. As soon as I find more, I'll let you know. Sorry for the delay.

[pcibin]

Thank you for your help.

[pcibin]

It was an error on the environment on my side but I fixed it, I'm closing the issue :)

[schen2643]

@pcibin Hello! I encountered the same error, would you mind sharing how you fixed it? Thank you!!

[ciaran-campbell]

Im having the same issue - has anyone worked out how to fix it?

[PoojaMiddha]

I am having the same issue. How did you all fixed it?