Error Estimating density between pairs of samples

[mdurante1]

Hi,

I recently encountered an error during the estimating density step between pairs of samples step (see error output below) when running one of our multi-sample cases. Any insight into what could be occurring would be greatly appreciated. Of note, there’s good overlap of mutations between the 2 samples.

I’m happy to provide any additional information requested. Thank you!

[1] "Loading data..."
[1] "Removed 0 with missing WTCount"
[1] "Removed 0 with missing mutCount"
[1] "Removed 610 with missing totalCopyNumber"
[1] "Removed 0 with missing copyNumberAdjustment"
[1] "Removed 476 with missing kappa"
[1] "Removed 0 with no coverage"
[1] "Removed 0 on not supported genomic regions"
[1] ""
[1] "Removed 610 mutations with missing data"
[1] ""
[1] "Running DPClust..."
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[1] "Estimating density between pairs of samples..."
[1] "Samples P2510T and P3298T"
Error in if (is.na(indices)) { : the condition has length > 1
Calls: RunDP ... DirichletProcessClustering -> Gibbs.subclone.density.est
Execution halted

[mdurante1]

Issue was solved by going back to original install on R 4.1.3. This error was only re-produced with R 4.2.3.