Running VirHostMatcher-Net with a personal genome list

WeiliWw / VirHostMatcher-Net

VirHostMatcher-Net: A network-based computational tool for predicting virus-host interactions.

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Running VirHostMatcher-Net with a personal genome list #22

Closed miczuppi closed 2 years ago

miczuppi commented 2 years ago

Hi, I have sequenced both the bacteriome and the phageome of my samples, and I would like to assess which bacteria in the sample is infected by which phage. I was then thinking to use VirHostMatcher-Net on my phages using, for the -l GENOME_LIST flag, a personal genome list created from my bacteriome. Would that be possible?

Thank you for your time.

Michele Zuppi

WeiliWw commented 2 years ago

Hi Michele,

Unfortunately the tool does not support adding new bacterial genomes. You will need to prepare the following data:

s2star between new bacterial genomes and the training set
BLAST and CRISPR matches between the new bacterial genomes and the phageome of interest

And then calculate the score with the formula and parameters.

Best, Weili