Closed sidiropoulos closed 3 years ago
Hi Nikos,
Thank you very much for this feedback! I think the reason might be that the chromosome names in your cool file do not have the prefix "chr", which was considered as "Invalid" when the program was trying to extract the GC/mappability content from the pre-calculated bigwig files.
I will make the program compatible with hic2cool
in the next version for sure. But for now, could you run the script "https://raw.githubusercontent.com/XiaoTaoWang/NeoLoopFinder/master/scripts/add_prefix_to_cool.py" on your cool files before calculate-cnv
(python add_prefix_to_cool.py inter_30.10kb.raw.cool), and let me know whether it works?
Thanks, Xiaotao
Hi Xiaotao,
Thank you for the very prompt reply. The fix you proposed worked and I could run calculate-cnv
successfully!
Looking forward to using the full toolkit.
Thanks, Nikos
Great, thanks!
Thank you for this very promising and much needed tool for cancer 3D genomics. I'm trying to run
calculate-cnv
on a 10kb cool matrix I created withhic2cool
and I get the following error.Do you have any idea of what could be causing the error?
Thanks, Nikos