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YangLab / CIRCexplorer

A combined strategy to identify circular RNAs (circRNAs and ciRNAs) (Zhang et al., Complementary Sequence-Mediated Exon Circularization, Cell (2014), 159:134-147)
http://yanglab.github.io/CIRCexplorer
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Lariat search #9

Closed akesarwani closed 8 years ago

akesarwani commented 8 years ago

Hi, I found CIRCexplore a very useful tool for detecting circRNA from RNA-seq. I am interested in detecting circRNA which completely falls in intron (=lariat sequence). I mapped the paired-end reads with tophat and executed this program in the same way as mentioned on github page, but I did not find circRNA associated with lariats, rather from exons. Can you suggest me if some how the tool can enforced to pic circ RNA only from introns.

Thanks.

kepbod commented 8 years ago

CIRCexplorer could detect circular intronic long noncoding RNAs (ciRNAs, lariat sequences as you mentioned above ), and these ciRNAs have been labeled in results.