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YeoLab / FLARE

RNA edit detection (SAILOR) and peak calling (FLARE)
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Sailor on paired-end data #3

Closed CelineLabbeCurie closed 2 months ago

CelineLabbeCurie commented 1 year ago

Hello,

I've used Sailor to find edit sites (C-to-U) but as I have paired-end data (at least I supposed it's because of that), Sailor output contains only editing on the minus strand et none on the plus strand. Is there a way to use Sailor on paired-end data please ?

Best regards

garifalloj commented 1 year ago

Hello,

I would also like to understand the best way to run paired-end data using SAILOR. I have been able to run the single-end data with the appropriate outputs. I believe in the previous version of the program, there was a configuration field for selecting single or paired-end, but I was not able to find the same editable field in the snakefile.

Thanks for any advice!

ekofman commented 2 months ago

SAILOR does not handle paired end data well (coverage is double-counted) currently. We are working on ways to make this available. Sorry for the delay in responding.