Closed PoGibas closed 1 year ago
My suggested way would be to run scanpy.tl.rank_genes_groups and use the respective column as grouping? Most classifiers (not the KNN and SCANVI) can report also intrinsic DE genes. Currently, this is not supported in PopV and we are waiting for a response of the OnClass authors to make their gene list accesible (as it contains unseen predictions it is in our perspective the most valuable one in addition of the final prediction where rank_genes_groups is the suggested method).
This is a question (feature request) regarding parsing
annotate_data
result.popv.annotation.annotate_data
provides assigned cell-type labels (e.g.,res.obs.popv_majority_vote_prediction
or for a single methodres.obs.popv_svm_prediction
). Is it possible to extract the most significant genes for a given label?For example:
Is it possible to get the genes rated by their importance for a specific label (e.g.,
plasma cell
)? I'm not sure if such information is even available withinPopV
or if I should look elsewhere for it.